Home Chemistry Organic Building Blocks Bromides 3-Bromobenzoic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Br,—COOH).
Sonogashira Coupling: Bromobenzene can undergo coupling reactions with terminal 【alkynes|https://www.ambeed.com/alkynyls.html】 using a palladium catalyst, leading to the formation of substituted 【alkynes|https://www.ambeed.com/alkynyls.html】.
Friedel-Crafts Acylation: Benzoic acid can undergo Friedel-Crafts acylation reactions with aromatic compounds in the presence of a Lewis acid catalyst such as aluminum chloride (AlCl3). This reaction results in the introduction of an acyl group (RCO-) onto the aromatic ring.
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3,6-Dibromobenzene-1,2,4,5-tetracarboxylic acid
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