Home Chemistry Organic Building Blocks Fluorinated Building Blocks 4-Fluorophenol
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—OH).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Reduction: Phenol can be reduced to form cyclohexanone or cyclohexanol using reducing agents.
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1-(4-Bromo-5-fluoro-2-hydroxyphenyl)ethanone
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(R)-2-(1-Aminoethyl)-4-fluorophenol hydrochloride
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4-Fluoro-2-[(methylamino)methyl]phenol
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