Home Chemistry Heterocyclic Building Blocks Pyrrolidines 4-Phenylpyrrolidin-2-One
Reductive Amination: PVP can undergo reductive amination with various primary or secondary amines to produce a range of substituted pyrrolidin-2-ones.
Ring-Opening: PVP's pyrrolidinone ring can be opened under appropriate conditions, leading to the formation of different compounds.
Reduction: PVP can be reduced to form the corresponding secondary amine or further reduced to the primary amine.
Halogenation: The phenyl ring in 4-phenylpyrrolidin-2-one can be halogenated with halogenating reagents like bromine or chlorine, leading to the formation of halogenated derivatives.
Mannich Reaction: PVP can undergo a Mannich reaction, which involves the condensation of amines, formaldehyde, and PVP to form β-amino carbonyl compounds.
Cyclization: Depending on reaction conditions and reagents, PVP can undergo various cyclization reactions to form different cyclic compounds.
Alkylation: PVP can be alkylated using alkyl halides or similar reagents to introduce alkyl substituents.
Oxidation: The carbonyl group in PVP can be oxidized to form corresponding carboxylic acids or other oxidation products.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
Ethyl 2-oxo-4-phenylpyrrolidine-3-carboxylate
click to sign in and save
4-(2-Chloro-6-fluorophenyl)pyrrolidin-2-one
click to sign in and save
2-(4-(4-Chlorophenyl)-2-oxopyrrolidin-1-yl)acetamide
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :