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Chemical Structure| 5851-43-4 Chemical Structure| 5851-43-4

Structure of 5851-43-4

Chemical Structure| 5851-43-4

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Product Details of [ 5851-43-4 ]

CAS No. :5851-43-4
Formula : C10H12N2
M.W : 160.22
SMILES Code : CC(C1=NC2=CC=CC=C2N1)C
MDL No. :MFCD00051759
InChI Key :RITUGMAIQCZEOG-UHFFFAOYSA-N
Pubchem ID :22121

Safety of [ 5851-43-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 5851-43-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 5851-43-4 ]

[ 5851-43-4 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 18362-64-6 ]
  • [ 95-54-5 ]
  • [ 5851-43-4 ]
YieldReaction ConditionsOperation in experiment
55% With sodium iodide dichloride; In tetrahydrofuran; water;Reflux; General procedure: To a mixture of o-substituted (-NH2 or -SH or -OH) anilines(1.0 mmol) and appropriate 1,3-diketones (1.1 mmol) in THF(5 mL) was added 30%w/w aqueous NaICl2 (0.2 mmol, 20mol%). The reaction was allowed to remain stirred at refluxtemperature for 2-3 h. After the reaction was complete, asindicated by TLC, the mixture was cooled to room temperature.The volatiles were removed under reduced pressureand treated successively with aqueous sodium thiosulphatesolution and saturated solution of NaHCO3, and extractedby ethylacetate (2×10 mL). The combined organic phaseswere washed with brine and dried over Na2SO4 and evaporatedunder vacuum. The crude reaction mixture was purifiedby column chromatography on silica gel using petroleumether/ethyl acetate as eluents.
  • 2
  • [ 67-56-1 ]
  • [ 1761-56-4 ]
  • [ 5851-43-4 ]
  • [ 6018-89-9 ]
  • [Ni(2-((2-oxybenzylidene)amino)phenolate)(2-iPr-benzim)]·MeOH [ No CAS ]
YieldReaction ConditionsOperation in experiment
76% In acetonitrile; for 2h;Reflux; General procedure: We added a solution of nickel(II) acetate tetrahydrate (0.497g; 0.002mol) in MeOH (30mL) and solid PPh3 (0.524g; 0.002mol) to a solution of Schiff base H2L (0.426g; 0.002mol) in MeCN (30mL). The resulting solution was refluxed for 2h and then left to evaporate slowly at ambient temperature. Well shaped red-brown crystals of complex 5a suitable for single crystal X-ray structure analysis were collected after few days by filtration, washed with methanol and finally dried at ambient temperature.
 

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