Home Chemistry Organic Building Blocks Alcohols Benzyl-2-(Hydroxymethyl)Pyrrolidine-1-Carboxylate
Ester Hydrolysis: The carboxylate group in the compound can undergo hydrolysis, typically in the presence of an acid or a base, to form the corresponding carboxylic acid and alcohols
Nucleophilic Substitution: The benzyl group is susceptible to nucleophilic substitution reactions, where the benzyl halide can be replaced with various nucleophiles (e.g., -OH, -SH, -NH2, etc.) to produce different derivatives.
Reduction: The carbonyl group in the ester can be reduced to an alcohol using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Oxidation: The alcohol group can be oxidized to an aldehyde or carboxylic acid using oxidizing agents like potassium permanganate (KMnO4) or Jones reagent.
Amide Formation: The amine group in the pyrrolidine ring can react with acid chlorides or anhydrides to form amides.
Esterification: The alcohol group can react with acid chlorides or anhydrides to form ester.
Grignard Reaction: The compound can react with a Grignard reagent to form a new carbon-carbon bond, typically in the presence of a suitable catalyst.
Acylation: The amine group can undergo acylation reactions to introduce acyl groups.
Alkylation: The amine group can be alkylated to introduce alkyl groups.
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(2R,4R)-Benzyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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(R)-Benzyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
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Benzyl (2S,4R)-4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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rel-(2R,4R)-Benzyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate hydrochloride
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(2R,4R)-Benzyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate hydrochloride
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(2S,4S)-1-Cbz-2-Hydroxymethyl-4-aminopyrrolidine hydrochloride
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(2R,4S)-Benzyl 4-amino-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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(2R,4S)-Benzyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate
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