Technical Information Amino Acids Lysine

Lysine

Lysine, represented by the symbol Lys or K, is an α-amino acid essential for the synthesis of many proteins. Lysine has a lysyl side chain ((CH2)4NH2), making it a basic, charged (at physiological pH), aliphatic amino acid. In nature, two distinct pathways have been identified for the synthesis of lysine. The diaminopimelate (DAP) pathway is classified under the aspartate-derived biosynthetic family, which is also responsible for the synthesis of threonine, methionine, and isoleucine. On the other hand, the α-aminoadipate (AAA) pathway is associated with the glutamate biosynthetic family. It is crucial for protein synthesis, contributing to the creation of new proteins in the body. Additionally, lysine plays a role in the crosslinking of collagen polypeptides, which provides strength and structure to various tissues. It is also involved in the uptake of essential mineral nutrients and plays a part in the production of carnitine, a molecule essential for fatty acid metabolism. The genetic code encodes lysine using the codons AAA and AAG.

Structure
CAS Number 56-87-1
Classification

The basic (positively charged) amino acids include

Arginine

Lysine

Histidine
Categories
Lysine biosynthesis Related Compounds 1
56-84-8 L-Aspartate
22138-53-0 4-Phospho-L-aspartate
L-Aspartate 4-semialdehyde
(2S,4S)-4-Hydroxy-2,3,4,5-tetrahydrodipicolinate
2,3,4,5-Tetrahydrodipicolinate
N-Acetyl-L-2-amino-6-oxopimelate
N6-Acetyl-LL-2,6-diaminoheptanedioate
LL-2,6-Diaminoheptanedioate
meso-2,6-Diaminoheptanedioate
56-87-1 L-Lysine
Lysine biosynthesis Related Compounds 2
328-50-7 2-Oxoglutarate
72-89-9 Acetyl-CoA
(R)-2-Hydroxybutane-1,2,4-tricarboxylate
(Z)-But-1-ene-1,2,4-tricarboxylate
Homoisocitrate
3184-35-8 2-Oxoadipate
542-32-5 L-2-Aminoadipate
L-2-Aminoadipate adenylate
alpha-Aminoadipoyl-S-acyl enzyme
L-2-Aminoadipate 6-semialdehyde
997-68-2 N6-(L-1,3-Dicarboxypropyl)-L-lysine
56-87-1 L-Lysine

Lysine and Derivatives:

Lysine:

Derivatives: