Sulfilimines: An Underexplored Bioisostere for Drug Design?

In the ever-evolving landscape of medicinal chemistry, searching for novel functional groups with optimized pharmacological properties remains a key driver of innovation. While sulfoximines have gained increasing traction as aza-analogs of sulfones in both FDA-approved drugs and agrochemicals, a newer class—sulfilimines—is now emerging as a promising, underutilized scaffold for drug design. Pioneering studies by Ellman, Gnamm, and most recently by Arvidsson and Ritter’s groups have demonstrated the chemical versatility, metabolic stability, and synthetic utility of sulfilimines in the development of bioactive molecules.

2025-04-21

World Cancer Day 2025: Breakthroughs and Trends in Anti-Cancer Drug Development

On World Cancer Day 2025, we reflect on the progress in cancer research, especially small-molecule drugs and precision medicine. Advances in AI and targeted therapies are transforming cancer care, and AmBeed proudly supports researchers driving these breakthroughs. Together, we move closer to a cancer-free future.

2025-02-04

Harnessing Photocatalytic Single-Electron Oxidation: Radical Precursors for Efficient Metallaphotoredox Couping Reactions

Elevate your photoredox catalysis with our premium radical precursors, meticulously crafted for efficient radical generation via single-electron oxidation! Explore our diverse product lineup, including carboxylic acids, alkylboron derivatives, 1,4-dihydropyridines, and more—ideal for metallaphotoredox systems and coupling reactions.

2025-01-17

World Mental Health Day 2024: Prioritizing Mental Health in the Workplace for a Healthier Future

On World Mental Health Day 2024, let's prioritize mental well-being in the workplace. With the theme "It is Time to Prioritize Mental Health in the Workplace," we aim to create inclusive environments where everyone can thrive. Take a moment to care for your mind and support your colleagues—together, we can build healthier, more productive workspaces.

2024-10-10

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