phenyl-indene | Ambeed

Chemistry Heterocyclic Building Blocks Thiophenes dihydrothiophen-3(2H)-one

dihydrothiophen-3(2H)-one

: Nucleophilic Addition: Dihydrothiophen-3(2H)-one is susceptible to nucleophilic addition reactions at the carbonyl (C=O) group. This can involve various nucleophiles such as amines, hydride sources (e.g., NaBH₄), and organometallic reagents (e.g., Grignard reagents). The outcome depends on the specific nucleophile and reaction conditions. Oxidation: The sulfur atom in dihydrothiophen-3(2H)-one can be oxidized to give sulfoxides or sulfones when treated with strong oxidizing agents like hydrogen peroxide (H₂O2) or peracids. Reduction: The carbonyl group can be reduced to the corresponding alcohol using reducing agents like sodium borohydride (NaBH₄) or lithium aluminum hydride (LiAlH₄). Acylation: Dihydrothiophen-3(2H)-one can undergo acylation reactions with acyl chlorides or anhydrides to form ketones or amides. Ring-Opening Reactions: Depending on the reaction conditions, dihydrothiophen-3(2H)-one can undergo ring-opening reactions to give linear or branched products. This can occur under acidic or basic conditions. Michael Addition: Dihydrothiophen-3(2H)-one can participate in Michael addition reactions with Michael acceptors, such as α,β-unsaturated carbonyl compounds, in the presence of a base. This leads to the addition of the thiolane-3-one to the double bond of the acceptor. Substitution Reactions: The halogenation of dihydrothiophen-3(2H)-one can occur, which can lead to the substitution of the sulfur atom with a halogen (e.g., chlorine or bromine). Heterocycle Formation: Dihydrothiophen-3(2H)-one can participate in the formation of other heterocyclic compounds by reaction with appropriate reagents, leading to the expansion or modification of the thiophene ring.

dihydrothiophen-3(2H)-one

A273149159531-97-297%

$290.00/25g

A335984245653-52-598%

$68.00/1g

A346851213381-88-597%

$62.00/1g

A3661983910-35-898%

$422.00/25g