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Chemical Structure| 66389-74-0 Chemical Structure| 66389-74-0

Structure of (+)-Apogossypol
CAS No.: 66389-74-0

Chemical Structure| 66389-74-0

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(+)-Apogossypol is a potent inhibitor of Bcl-2 family proteins and competes with the BH3 peptide-binding sites on Bcl-2, Bcl-XL, Mcl-1, Bcl-W, and Bcl-B, but not Bfl-1, with IC50s of 0.5 to 2 μM.

Synonyms: NSC736630; Apogossypol

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Product Details of (+)-Apogossypol

CAS No. :66389-74-0
Formula : C28H30O6
M.W : 462.53
SMILES Code : OC1=C(O)C(C(C)C)=C2C=C(C)C(C3=C(C)C=C4C(C(C)C)=C(O)C(O)=CC4=C3O)=C(O)C2=C1
Synonyms :
NSC736630; Apogossypol
MDL No. :MFCD23160033

Safety of (+)-Apogossypol

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.16mL

0.43mL

0.22mL

10.81mL

2.16mL

1.08mL

21.62mL

4.32mL

2.16mL

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