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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 200801-70-3 Chemical Structure| 200801-70-3

Structure of 200801-70-3

Chemical Structure| 200801-70-3

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(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) is an active metabolite of Tolterodine, an mAChR antagonist with Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively, used in the study of overactive bladder.

Synonyms: (Rac)-Desfesoterodine; (Rac)-PNU-200577

4.5 *For Research Use Only !

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Product Details of (Rac)-5-Hydroxymethyl Tolterodine

CAS No. :200801-70-3
Formula : C22H31NO2
M.W : 341.49
SMILES Code : OC1=CC=C(CO)C=C1C(C2=CC=CC=C2)CCN(C(C)C)C(C)C
Synonyms :
(Rac)-Desfesoterodine; (Rac)-PNU-200577
MDL No. :MFCD09840742
InChI Key :DUXZAXCGJSBGDW-UHFFFAOYSA-N
Pubchem ID :9927971

Safety of (Rac)-5-Hydroxymethyl Tolterodine

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H319-H360
Precautionary Statements:P201-P202-P264-P270-P280-P281-P301+P312-P305+P351+P338-P308+P313-P330-P337+P313-P405-P501
Class:6.1
UN#:2811
Packing Group:

Isoform Comparison

Biological Activity

Description
(Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, acts as a muscarinic acetylcholine receptor (mAChR) antagonist with Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively. This compound is utilized in research related to overactive bladder[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.93mL

0.59mL

0.29mL

14.64mL

2.93mL

1.46mL

29.28mL

5.86mL

2.93mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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