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Chemical Structure| 67920-52-9 Chemical Structure| 67920-52-9

Structure of (Rac)-Salvianic acid A sodium
CAS No.: 67920-52-9

Chemical Structure| 67920-52-9

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Sodium danshensu is a mono sodium of danshensu, which is a natural phenolic acid of caffeic acid derivatives isolated from Salvia miltiorrhiza.

Synonyms: (Rac)-Danshensu sodium; (Rac)-Tanshinol sodium; Danshensu sodium

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Product Details of (Rac)-Salvianic acid A sodium

CAS No. :67920-52-9
Formula : C9H9NaO5
M.W : 220.15
SMILES Code : O=C([O-])C(O)CC1=CC=C(O)C(O)=C1.[Na+]
Synonyms :
(Rac)-Danshensu sodium; (Rac)-Tanshinol sodium; Danshensu sodium
MDL No. :MFCD09037393
InChI Key :ZMMKVDBZTXUHFO-UHFFFAOYSA-M
Pubchem ID :23711819

Safety of (Rac)-Salvianic acid A sodium

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
ACE2-overexpressed HEK-293T cells 0.31 μM (IC50) 12 hours Evaluate the inhibitory effect of Danshensu on SARS-CoV-2 S protein-mediated virus entry, results showed Danshensu effectively inhibited virus entry PMC8280584
Vero-E6 cells 0.97 μM (EC50) 24 hours Evaluate the antiviral activity of Danshensu against SARS-CoV-2, results showed Danshensu effectively inhibited viral replication PMC8280584
Ca9-22 cells 25, 50, 100 µM 24, 48, 72 hours Assessed cytotoxicity, results showed no cytotoxicity PMC7554528
FaDu cells 25, 50, 100 µM 24, 48, 72 hours Assessed cytotoxicity, results showed no cytotoxicity PMC7554528
Rat aortic VSMC cell line A10 0-100 μM SalA and SalB reduce homocysteine-induced ROS production by inhibiting the activation of protein kinase C and p44/42 MAP kinase. PMC7533016

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

4.54mL

0.91mL

0.45mL

22.71mL

4.54mL

2.27mL

45.42mL

9.08mL

4.54mL

References

 

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