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Chemical Structure| 199596-24-2 Chemical Structure| 199596-24-2

Structure of (Z)-JIB-04
CAS No.: 199596-24-2

Chemical Structure| 199596-24-2

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(Z)-JIB-04 is the Z isomer of JIB-04, which has potential in certain epigenetic studies. It has application value in regulating cell signaling, although it may exhibit lower activity in some cases.

Synonyms: NSC693627; JIB-04 Z-isomer; JIB-04 Z-isomer, NSC-693627

4.5 *For Research Use Only !

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Product Details of (Z)-JIB-04

CAS No. :199596-24-2
Formula : C17H13ClN4
M.W : 308.76
SMILES Code : ClC1=CN=C(C=C1)N/N=C(C2=NC=CC=C2)/C3=CC=CC=C3
Synonyms :
NSC693627; JIB-04 Z-isomer; JIB-04 Z-isomer, NSC-693627
MDL No. :MFCD28347704

Safety of (Z)-JIB-04

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H311-H331
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Related Pathways of (Z)-JIB-04

epigenetics

Isoform Comparison

Biological Activity

Target
  • KDM4

    JMJD2A, IC50:1100 nM

    JMJD2E, IC50:340 nM

  • KDM6

    JMJD3, IC50:855 nM

  • KDM5

    JARID1A, IC50:230 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.24mL

0.65mL

0.32mL

16.19mL

3.24mL

1.62mL

32.39mL

6.48mL

3.24mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2
 

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