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Chemical Structure| 1159588-21-2 Chemical Structure| 1159588-21-2

Structure of (Z)-Pitavastatin calcium
CAS No.: 1159588-21-2

Chemical Structure| 1159588-21-2

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(Z)-Pitavastatin calcium is the Z-isomer of Pitavastatin calcium, an effective HMG-CoA reductase inhibitor with an IC50 of 5.8 nM in inhibiting acetate-induced cholesterol synthesis in HepG2 cells.

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Product Details of (Z)-Pitavastatin calcium

CAS No. :1159588-21-2
Formula : C50H46CaF2N2O8
M.W : 880.98
SMILES Code : FC1=CC=C(C2=C(C(C3CC3)=NC4=C2C=CC=C4)/C=C\[C@H](C[C@H](CC([O-])=O)O)O)C=C1.FC5=CC=C(C6=C(C(C7CC7)=NC8=C6C=CC=C8)/C=C\[C@H](C[C@H](CC([O-])=O)O)O)C=C5.[Ca+2]
MDL No. :N/A

Safety of (Z)-Pitavastatin calcium

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H361-H362
Precautionary Statements:P501-P263-P260-P270-P202-P201-P264-P280-P308+P313-P301+P312+P330-P405

Isoform Comparison

Biological Activity

Description
(Z)-Pitavastatin calcium is the Z-isomer of Pitavastatin hemicacium. It functions as a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor, effectively inhibiting cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells [1].

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1 mM

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1.14mL

0.23mL

0.11mL

5.68mL

1.14mL

0.57mL

11.35mL

2.27mL

1.14mL

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