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Chemical Structure| 874-14-6 Chemical Structure| 874-14-6
Chemical Structure| 874-14-6

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1,3-Dimethyluracil is a methyl derivative of uric acid, found occasionally in human urine.

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Product Details of 1,3-Dimethyluracil

CAS No. :874-14-6
Formula : C6H8N2O2
M.W : 140.14
SMILES Code : CN1C=CC(=O)N(C)C1=O
MDL No. :MFCD00038065
InChI Key :JSDBKAHWADVXFU-UHFFFAOYSA-N
Pubchem ID :70122

Safety of 1,3-Dimethyluracil

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 1,3-Dimethyluracil

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 874-14-6 ]

[ 874-14-6 ] Synthesis Path-Downstream   1~10

  • 1
  • [ 1122-12-9 ]
  • [ 874-14-6 ]
  • [ 52695-25-7 ]
  • 3
  • [ 7033-39-8 ]
  • [ 75-24-1 ]
  • [ 874-14-6 ]
  • [ 4401-71-2 ]
  • 4
  • [ 75-24-1 ]
  • [ 31217-00-2 ]
  • [ 874-14-6 ]
  • [ 4401-71-2 ]
  • 5
  • [ 75-24-1 ]
  • [ 40738-83-8 ]
  • [ 874-14-6 ]
  • [ 4401-71-2 ]
  • 7
  • [ 874-14-6 ]
  • [ 55270-33-2 ]
  • [ 1493-13-6 ]
  • C16H13F3IN3O5S [ No CAS ]
  • 8
  • [ 874-14-6 ]
  • [ 1203705-55-8 ]
  • (2-bromopyrazolo[1,5-a]pyrimidin-5-yl)oxysodium [ No CAS ]
YieldReaction ConditionsOperation in experiment
38% With sodium; at 80.0℃; for 3.0h; To a solution of Na (7.10 g, 309 mmol) in EtOH (125 mL) was added <strong>[1203705-55-8]3-bromo-1H-pyrazol-5-amine</strong> (5.00 g, 30.9 mmol, CAS1203705-55-8) and 1,3-dimethylpyrimidine-2,4-dione (4.33 g, 30.9 mmol, CAS874-14-6). The reaction mixture was stirred at 80 C. for 3 hours. On completion, the mixture was cooled to 0-5 C., then filtered. The filter cake was washed with cold EtOH, and dried in vacuo to give the title compound (2.80 g, 38% yield) as a yellow solid. 1H NMR (400 MHz, D2O) delta 8.02 (d, J=7.6 Hz, 1H), 5.98 (d, J=7.6 Hz, 1H), 5.85 (s, 1H).
  • 9
  • [ 874-14-6 ]
  • [ 104-15-4 ]
  • [ 175278-00-9 ]
  • C13H11F3IN2O3(1+)*C7H7O3S(1-) [ No CAS ]
YieldReaction ConditionsOperation in experiment
56% With 3-chloro-benzenecarboperoxoic acid; at 20℃; General procedure: To a solution of 1,3-dimethyluracil 1a (0.20 mmol) in 2,2,2-trifluoroethanol (TFE) (3 mL), (4-chlorophenyl)(hydroxy)iodonium tosylate 2f (0.22 mmol) was added and it was stirred at room temperature. After completion of the reaction, the solvent was removed under vacuum. The product was then precipitated by the addition of Et2O with stirring. The precipitate was filtered to give uracil-iodonium(III) salt 3af-OTs as a white powder.
  • 10
  • [ 874-14-6 ]
  • [ 802919-90-0 ]
  • 5-(difluoro(phenylsulfonyl)methyl)-1,3-dimethylpyrimidine-2,4-(1H,3H)-dione [ No CAS ]
 

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