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Chemical Structure| 24463-15-8 Chemical Structure| 24463-15-8
Chemical Structure| 24463-15-8

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1-Hydroxymethylpyrene is a pyrene derivative commonly used as a fluorescent probe in biological and chemical analyses, capable of interacting with various molecules and emitting strong fluorescence.

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Product Details of 1-Hydroxymethylpyrene

CAS No. :24463-15-8
Formula : C17H12O
M.W : 232.28
SMILES Code : OCC1=C(C2=C34)C=CC4=CC=CC3=CC=C2C=C1
MDL No. :MFCD00029252
InChI Key :NGDMLQSGYUCLDC-UHFFFAOYSA-N
Pubchem ID :104977

Safety of 1-Hydroxymethylpyrene

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of 1-Hydroxymethylpyrene

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 24463-15-8 ]

[ 24463-15-8 ] Synthesis Path-Downstream   1~2

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  • [ 24463-15-8 ]
  • [ 68631-52-7 ]
  • [ 701937-57-7 ]
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  • [ 6964-21-2 ]
  • [ 24463-15-8 ]
  • pyren-1-ylmethyl 2-(thiophen-3-yl)acetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
65% With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 - 20℃; for 12.5h;Inert atmosphere; General procedure: General SynthesisThe appropriate thiophene alcohol (0.82 mmol), the selected carboxylic acid (1.23 mmol), DCC(2.46 mmol) and DMAP (2.05 mmol) were dissolved in CH2Cl2 (15 mL) at 0 C for 30 min. The resultingmixture was stirred at room temperature for 12 h under inert atmosphere. The suspension was filteredin order to remove DCU formed during the reaction, and the filtrates were concentrated under reducedpressure at 45 C. The crude product was purified by column chromatography in silica gel, usingn-hexane/CH2Cl2 (2:5) and then pure CH2Cl2 as eluent to give the desired product TPM1 (Figure 1).All monomers were characterized by 1H- and 13C-NMR spectroscopy and the spectra are included inthe Supplementary Materials.
 

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