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Chemical Structure| 96-27-5 Chemical Structure| 96-27-5
Chemical Structure| 96-27-5

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Synonyms: alpha-Thioglycerol; 3-Mercaptopropane-1,2-diol; 1-Thio-2,3-propanediol

4.5 *For Research Use Only !

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Product Details of 1-Thioglycerol

CAS No. :96-27-5
Formula : C3H8O2S
M.W : 108.16
SMILES Code : SCC(CO)O
Synonyms :
alpha-Thioglycerol; 3-Mercaptopropane-1,2-diol; 1-Thio-2,3-propanediol
MDL No. :MFCD00004879
InChI Key :PJUIMOJAAPLTRJ-UHFFFAOYSA-N
Pubchem ID :7291

Safety of 1-Thioglycerol

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H302-H311-H315-H319-H335
Precautionary Statements:P261-P280-P305+P351+P338-P312
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of 1-Thioglycerol

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 96-27-5 ]

[ 96-27-5 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 26305-75-9 ]
  • [ 96-27-5 ]
  • bis{(3-mercapto-1,2-propanediol)bis(triphenylphosphine)cobalt(I)} [ No CAS ]
  • 2
  • [ 51792-34-8 ]
  • [ 96-27-5 ]
  • (2,3-dihydrothieno[3,4-b][1,4]oxathiin-2-yl)methanol [ No CAS ]
  • 3
  • [ 96-27-5 ]
  • [ 69655-76-1 ]
  • [ 1383079-34-2 ]
  • 4
  • [ 96-27-5 ]
  • [ 69655-76-1 ]
  • C40H88O28S8Si8 [ No CAS ]
YieldReaction ConditionsOperation in experiment
61% With 2,2-dimethoxy-2-phenylacetophenone; In tetrahydrofuran; at 20℃; for 0.25h;UV-irradiation; In a vial, OVS (0.5g, 0.79mmol), 1.1equiv (to ?Vi groups) of 1?thioglycerol (0.70g, 6.95mmol) and 2wtpercent of DMPA were dissolved in the minimal amount of THF. The mixture was irradiated with stirring for 15min with UV light at room temperature and then concentrated under reduced pressure [26]. The crude product was washed by ethyl acetate and the residual solvent was removed under vacuum overnight at room temperature. The SQ?[OH]16 was obtained as a white powder (0.72g, yield 61percent). 1H NMR (300MHz, CD3OD?d4, ppm): delta=1.01?1.11 (t, ?SiCH2CH2, J=8.2Hz, 16H), 2.57?2.78 (m, ?CH2SCH2, 32H), 3.54?3.66 (m, ?CH2OH, 16H), 3.73?3.81 (m, ?CHOH, 8H); 13C NMR (75MHz, CD3OD?d4, ppm): delta=13.8 (?SiCH2CH2?), 27.7 (?SiCH2CH2?), 36.1(?SCH2CH?), 66.0 (?CH2OH), 72.8 (?CHOH). 29Si NMR (59Hz, CD3OD?d4, ppm): delta=?64.45. FTIR (KBr, cm?1): 3368, 2963, 2876, 2560, 1093, 1032. MS?ESI: 1520.12 [M+Na]+, 1479.13 [M?H2O]+. Anal. Calcd for C40H88O28S8Si8: C, 32.06; H, 5.92; S, 17.12. Found: C, 31.99, H, 5.87; S, 17.01. Tm: 118°C.
  • 5
  • [ 106-86-5 ]
  • [ 96-27-5 ]
  • 3-[2-(7-oxa-bicyclo[4.1.0]hept-3-yl)-ethylsulfanyl]-propane-1,2-diol [ No CAS ]
  • 6
  • [ 96-27-5 ]
  • [ 69655-76-1 ]
  • C32H72O28S8Si8 [ No CAS ]
 

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