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Chemical Structure| 1007568-39-9 Chemical Structure| 1007568-39-9

Structure of 1007568-39-9

Chemical Structure| 1007568-39-9

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Product Details of [ 1007568-39-9 ]

CAS No. :1007568-39-9
Formula : C16H13NO6
M.W : 315.28
SMILES Code : O=C(C1=CC=C(C2=CC=C(C(OC)=O)C=C2[N+]([O-])=O)C=C1)OC

Safety of [ 1007568-39-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1007568-39-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1007568-39-9 ]

[ 1007568-39-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 792-74-5 ]
  • [ 1007568-39-9 ]
YieldReaction ConditionsOperation in experiment
With nitric acid; trifluoroacetic anhydride; In water; trifluoroacetic acid; at 0℃; for 4.5h; A sample of 4,4'-biphenyldicarboxylate dimethyl ester, 2.0 g, was place in a 50 ml 2 neck 24/40 flask with stirring bar. Then trifluoroacetic acid, 10 ml, was added, and the mix was cooled to 0 0C. The cooled mixture was treated with 90% nitric acid, 0.38 ml, and then trifluoroacetic anhydride , 1.91 ml was added dropwise. TLC with 1 :8 ethyl acetate/hexanes on silica ant 30 minutes post TFAA showed some SM, and a new lower RF product. The mix was stirred 1 hour at 0 0C, then 3 hours at room temperature. The mixture was then poured into 100 ml of cold water, giving a gummy precipitate. The mix was treated with 80 ml of ethyl acetate and 20 ml of hexanes. The layers were separated, and the organic layer was washed with 100 ml of water. The organic layer was then stirred with 20 g of sodium bicarbonate in 100 ml of water. The ethyl acetate was evaporated in vacuo. The residue was treated with 100 ml of hexanes, heated to a boil, and diluted with ethyl acetate hot until a solution was obtained, then hexanes was added to a total volume of 200 ml. The mix was cooled to room temperature, and the resulting solids were collected by filtration, washed with 10 <n="73"/>ml hexanes, and air dried to give 2-nitro-4,4'-biphenyldicarboxylate dimethyl ester, 1.319 g.NMR 500 MH D6DMS0: 8.51, d, J=IJ, IH, 8.31, dd, J=U, 8.1, IH, 8.06, dd, J=1.8, 8.3, 2H, 7.76, d, J=8, IH, 7.56, dd, J=1.8, 8.4, 2H, 3.94, s, 3H, 3.89, s, 3H
 

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