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Chemical Structure| 1008769-62-7 Chemical Structure| 1008769-62-7

Structure of 1008769-62-7

Chemical Structure| 1008769-62-7

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Product Details of [ 1008769-62-7 ]

CAS No. :1008769-62-7
Formula : C12H13F3O3
M.W : 262.23
SMILES Code : O=C(O)C1=CC=C(OCC(C)C)C(C(F)(F)F)=C1
MDL No. :MFCD18991008

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Application In Synthesis of [ 1008769-62-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1008769-62-7 ]

[ 1008769-62-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 78-83-1 ]
  • [ 67515-55-3 ]
  • [ 1008769-62-7 ]
YieldReaction ConditionsOperation in experiment
With sodium hydride; In N,N-dimethyl-formamide; at 80℃; for 3h; Reference Example 20 4-isobutoxy-3-(trifluoromethyl)benzoic acid To an N,N-dimethylformamide solution (2 mL) of <strong>[67515-55-3]4-fluoro-3-(trifluoromethyl)benzoic acid</strong> (100 mg, manufactured by Fluorochem) and isobutanol (118 mg, manufactured by Tokyo Chemical Industry Co., Ltd.), sodium hydride (G2 mg, manufactured by Wako Pure Chemical Industries, Ltd.) was added. The resultant mixture was stirred for 3 hours at 80 C. After the stirring was ended, 1N HCl aqueous solution (2 mL, manufactured by Wako Pure Chemical Industries, Ltd.) was added to the reaction solution, and extraction was performed by using dichloromethane. An organic layer was dried by using magnesium sulfate, and concentrated under a reduced pressure, so that the titled compound (155 mg) was obtained. ESI-MS: 261.2 (M-H), RTime 4.80 min.
 

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