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Chemical Structure| 1019000-51-1 Chemical Structure| 1019000-51-1

Structure of DLinDAP
CAS No.: 1019000-51-1

Chemical Structure| 1019000-51-1

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Product Details of [ 1019000-51-1 ]

CAS No. :1019000-51-1
Formula : C41H73NO4
M.W : 644.02
SMILES Code : C(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COC(CCCCCCC/C=C\C/C=C\CCCCC)=O)CN(C)C
MDL No. :N/A

Safety of [ 1019000-51-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1019000-51-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1019000-51-1 ]

[ 1019000-51-1 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 60-33-3 ]
  • [ 623-57-4 ]
  • [ 1019000-51-1 ]
YieldReaction ConditionsOperation in experiment
22% With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20℃; To a solution of the linoleic acid (25 g, 89.1 mmol) in anhydrous DMF (60 mL), diisopropyl ethylamine (17 mL, 100 mml) was added at room temperature with stirring followed by <strong>[623-57-4]3-(dimethylamino)-1,2-propanediol</strong> (4.8 g , 40.5 mmol) and EDCI (17.25 g, 89.9 mmol) and the mixture was stirred at room temperature overnight. The TLC of the reaction mixture (eluent 20percent EtOAc in hexanes) showed the completion of the reaction. The reaction mixture was poured into ice water and extracted with ethyl acetate (2 x <n="133"/>100 mL). The combined organic layers were washed with water (100 mL), saturated NaHCO3 (100 mL) and dried over Na2SO4. Concentration of the organic layer provided the crude product which was purified by column chromatography (silica gel, eluent: 20percent EtOAc in hexanes). The fractions containing pure product was pooled and concentrated. The pure ester was isolated as a clear liquid (5.7 g, 22percent). MS m/z 645 (M+H). 1H NMR CDCl3 delta 0.88 (t,J= 6.3Hz, 6H), 1.20-1.39 (m, 28H), 1.61 (t, J = 4.9 Hz, 12H), 2.03-2.08 (m, 8H), 2.26-2.38 (m, 10H), 2.44-2.56 (m, 2H), 2.76 (t, J= 6.3 Hz, 4 H), 4.09 (dd, J= 6.1 Hz 11.9 Hz, 1H), 4.36 (dd, J= 3.3 11.9 Hz, 1H), 5.29-5.34 (m, 1H), 5.34-5.41 (m, 8H). 13C NMR CDCl3 delta 14.30, 22.79, 25.08, 25.10, 25.83, 27.40, 29.26, 29.30, 29.34, 29.42, 29.55, 29.83, 31.73, 34.32, 34.58, 46.01, 59.37, 64.02, 128.08, 128.24, 130.21, 130.42, 173.39, 173.65.
  • 2
  • [ 623-57-4 ]
  • [ 1019000-51-1 ]
 

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