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Chemical Structure| 10203-89-1 Chemical Structure| 10203-89-1

Structure of 10203-89-1

Chemical Structure| 10203-89-1

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Product Details of [ 10203-89-1 ]

CAS No. :10203-89-1
Formula : C7H17NO
M.W : 131.22
SMILES Code : CC(C)C[C@H](NC)CO
MDL No. :MFCD19217154

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Application In Synthesis of [ 10203-89-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10203-89-1 ]

[ 10203-89-1 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 66866-69-1 ]
  • [ 10203-89-1 ]
YieldReaction ConditionsOperation in experiment
97% With lithium aluminium tetrahydride; In tetrahydrofuran;Reflux; To a solution of <strong>[66866-69-1](S)-4-methyl-2-(methylamino)pentanoic acid hydrochloride</strong> salt (11, 5.0 g, 27.5 mmol) in dry THF (20 mL) was added lithium aluminium hydride (LAH) (33.0 mmol, 1 M solution in THF) dropwise at 5 C. The reaction mixture was refluxed for overnight and cooled to -5 C. Unreacted LAH was quenched with aq NaOH (0.8 g, 20.0 mmol, 2 N) and the mixture was stirred at room temperature for additional 30 min. The mixture was filtered, and was washed with diethyl ether (100 mL). The filtrate was dried over MgSO4 and solvent was removed under reduced pressure to obtain the product as colorless oil (3.5 g, 26.2 mmol, 97.0%). The product was analyzed by NMR and LC-MS and used in the next step without further purification.
 

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