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Chemical Structure| 102440-03-9 Chemical Structure| 102440-03-9

Structure of 102440-03-9

Chemical Structure| 102440-03-9

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Product Details of [ 102440-03-9 ]

CAS No. :102440-03-9
Formula : C9H14ClNO
M.W : 187.67
SMILES Code : NC1=C(C)C=C(OC)C=C1C.[H]Cl

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Application In Synthesis of [ 102440-03-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 102440-03-9 ]

[ 102440-03-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1336-21-6 ]
  • [ 60-29-7 ]
  • [ 61019-03-2 ]
  • [ 102440-03-9 ]
  • [ 142-04-1 ]
YieldReaction ConditionsOperation in experiment
With hydrogenchloride; zinc; In dichloromethane; water; acetic acid; toluene; Step 2 2,6-dimethyl-4-methoxyaniline hydrochloride 150 ml of glacial acetic acid are cautiously added dropwise to a refluxing mixture of <strong>[61019-03-2]3,5-dimethyl-4-nitroanisole</strong> (32.4 g) and 47.07 grams of zinc dust in 100 ml of toluene. The reaction is allowed to reflux for another two hours and allowed to cool. The reaction mixture is filtered and concentrated in vacuo to a dark oil which is taken up in 400 ml of CH2 Cl2 and washed with 50 ml of concentrated ammonium hydroxide and 800 ml of water. The organic layer is dried, filtered and concentrated in vacuo. The resulting dark oil is dissolved in ether. HCl/Et2 O is added to form a precipitate which is collected and dried to give 29.28 grams of the aniline hydrochloride, M.P. 228-232 C.
 

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