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Chemical Structure| 1027035-76-2 Chemical Structure| 1027035-76-2

Structure of 1027035-76-2

Chemical Structure| 1027035-76-2

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Product Details of [ 1027035-76-2 ]

CAS No. :1027035-76-2
Formula : C10H13NO3
M.W : 195.22
SMILES Code : O=C(OC)C1=CC=C(CN)C=C1OC
MDL No. :MFCD20703133

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Application In Synthesis of [ 1027035-76-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1027035-76-2 ]

[ 1027035-76-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 406719-76-4 ]
  • [ 1027035-76-2 ]
YieldReaction ConditionsOperation in experiment
34.7% With hydrogen;Raney-nickel; In methanol; water; under 2585.81 Torr; for 16.0h; A mixture of <strong>[406719-76-4]4-cyano-2-methoxy-benzoic acid methyl ester</strong> (1.01 g, 5.28 mmol) in methanol (50 mL) was added to Raney-nickel 2800 slurry in water (a few grams washed with methanol to remove the water, Aldrich) and it was put under a 50 psi hydrogen atmosphere for 16 hrs. The mixture was filtered through Celite under an argon atmosphere and concentrated and then purified by flash chromatography to give 4-aminomethyl-2-methoxy-benzoic acid methyl ester (385.7 mg, 34.7%).
 

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