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Chemical Structure| 104654-69-5 Chemical Structure| 104654-69-5

Structure of 104654-69-5

Chemical Structure| 104654-69-5

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Product Details of [ 104654-69-5 ]

CAS No. :104654-69-5
Formula : C10H16O2
M.W : 168.23
SMILES Code : O=C(C1=C(C)CCCC1)OCC

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Application In Synthesis of [ 104654-69-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 104654-69-5 ]

[ 104654-69-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 917-54-4 ]
  • [ 122135-83-5 ]
  • [ 104654-69-5 ]
YieldReaction ConditionsOperation in experiment
General procedure: To a stirred solution of CuCN (20.3 mmol, 1.80g, 1.4 eq) in dry 40 mL of Et2O under an N2 atmosphere at -50 C was added a solution of methyllithium (20.3 mmol, 1.6 M in diethyl ether,12.7 mL, 1.4 eq) dropwise. The reaction mixture was stirred at -50 C for 30 min and a solution of triflate (14.5 mmol, 5.52g, 1.0eq) in dry 10 mL of Et2O was added dropwise. The solution again was stirred at -50 C for 30 min. The reaction mixture was quenched with an ammonia solution of NH4Cl solid, and it was filtered over Celite and the aqueous layer was extracted with ethyl acetate. The combined organic layer was washed with water, brine and dried over Na2SO4. Evaporation of the solvent gave the ester product (2.30 g, 75% yield) which was carried to the next step without further purification.
 

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