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[ CAS No. 107960-02-1 ] {[proInfo.proName]}

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2D 3D

Chemical Structure| 107960-02-1

Chemical Structure| 107960-02-1

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Quality Control of [ 107960-02-1 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 107960-02-1 ]

Product Details of [ 107960-02-1 ]

CAS No. :	107960-02-1	MDL No. :
Formula :	C₇H₅Cl₄NO₅	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	-
M.W :	324.93	Pubchem ID :	-
Synonyms :

Safety of [ 107960-02-1 ]

Signal Word:		Class:
Precautionary Statements:		UN#:
Hazard Statements:		Packing Group:

Application In Synthesis of [ 107960-02-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 107960-02-1 ]
Downstream synthetic route of [ 107960-02-1 ]

[ 107960-02-1 ] Synthesis Path-Upstream 1~6

1
[ 15761-38-3 ]
[ 107960-02-1 ]
[ 3392-05-0 ]

Yield	Reaction Conditions	Operation in experiment
94%	With 4-methyl-morpholine In tetrahydrofuran; ethyl acetate; Petroleum ether	EXAMPLE 11: PREPARATION OF N-SUCCINIMIDYL N-TERT-BUTYLOXYCARBONYL-L-ALANINATE 0.95 g (5 mmol) of N-tert-butyloxycarbonyl-L-alanine and 0.66 ml (5.5 mmol) of N-methylmorpholine are dissolved in 6 ml of THF, and 1.8 g (5.5 mmol) of N-succinimidyl 1,2,2,2-tetrachloroethyl carbonate is added in a single portion. The mixture is stirred for two hours at 20° C. Approximately 25 ml of ethyl acetate are added and the organic phase is washed rapidly with N HCl solution, then with potassium bicarbonate solution and finally twice with water. The organic phase is dried over magnesium sulphate and evaporated. The residue is crystallized in an ethyl acetate/petroleum ether mixture and 1.25 g (Y=87percent) of white crystals are obtained. Evaporation of the mother liquors and crystallisation enables a further 0.1 g to be recovered, and this brings the yield to 94percent. M.p. (melting point)=158° C. [α]_D²⁰ =50.7 (c=2, dioxane)

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367
[2] Patent: US4782164, 1988, A,

2
[ 13734-34-4 ]
[ 107960-02-1 ]
[ 3674-06-4 ]

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367

3
[ 4530-20-5 ]
[ 107960-02-1 ]
[ 3392-07-2 ]

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367

4
[ 13734-41-3 ]
[ 107960-02-1 ]
[ 3392-12-9 ]

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367

5
[ 1138-80-3 ]
[ 107960-02-1 ]
[ 2899-60-7 ]

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367

6
[ 2389-45-9 ]
[ 107960-02-1 ]
[ 34404-36-9 ]

Reference： [1] Journal of Organic Chemistry, 1987, vol. 52, # 12, p. 2364 - 2367

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P378
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P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
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P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
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P401
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H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
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H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
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H242	Heating may cause a fire
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H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
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H281	Contains refrigerated gas; may cause cryogenic burns or injury
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Code	Phrase
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H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
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H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
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H316	Causes mild skin irritation
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