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Chemical Structure| 1103394-64-4 Chemical Structure| 1103394-64-4

Structure of 1103394-64-4

Chemical Structure| 1103394-64-4

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Product Details of [ 1103394-64-4 ]

CAS No. :1103394-64-4
Formula : C9H6N2O3
M.W : 190.16
SMILES Code : O=C(O)C1=CN=C(C2=CN=CO2)C=C1

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Application In Synthesis of [ 1103394-64-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1103394-64-4 ]

[ 1103394-64-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 38622-91-2 ]
  • [ 10165-86-3 ]
  • [ 1103394-64-4 ]
YieldReaction ConditionsOperation in experiment
With sodium methylate; In methanol;Heating / reflux; a suspension of methyl 6-formylnicotinate (60 mg, 0.363 mmol) in methanol (3 mL) was added sodium methoxide in methanol (0.5M, 2.91 mL, 1.45 mmol). Tosylmethyl isocyanide (85 mg, 0.436 mmol) was added to the reaction and the mixture was heated at reflux overnight.After cooling, the reaction mixture was concentrated. The residue was treated with 5percent citric acid/50percent brine (1:1) and extracted with ethyl acetate. The suspension was filtered, washed with water, and dried under vacuum to provide the title compound. MS (DCI/NH3) m/z: 191.0 (M+1)+.
 

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