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Chemical Structure| 110480-83-6 Chemical Structure| 110480-83-6

Structure of 110480-83-6

Chemical Structure| 110480-83-6

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Product Details of [ 110480-83-6 ]

CAS No. :110480-83-6
Formula : C12H13NO
M.W : 187.24
SMILES Code : OC[C@H](N)C1=C2C=CC=CC2=CC=C1
English Name :(R)-2-Amino-2-(naphthalen-1-yl)ethan-1-ol
MDL No. :MFCD09253739
InChI Key :GIJHQOMBLOZMEG-LBPRGKRZSA-N
Pubchem ID :10241558

Safety of [ 110480-83-6 ]

Application In Synthesis of [ 110480-83-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 110480-83-6 ]

[ 110480-83-6 ] Synthesis Path-Downstream   1~8

  • 1
  • [ 142758-91-6 ]
  • [ 110480-83-6 ]
YieldReaction ConditionsOperation in experiment
99% With 1,5-diamino-3-azapentane In neat (no solvent) for 18h;
  • 2
  • [ 7321-55-3 ]
  • [ 110480-83-6 ]
  • [ 635680-74-9 ]
YieldReaction ConditionsOperation in experiment
74% With zinc trifluoromethanesulfonate In toluene Reflux;
  • 3
  • [ 615-20-3 ]
  • [ 110480-83-6 ]
  • [ 1415839-26-7 ]
YieldReaction ConditionsOperation in experiment
21% Stage #1: 2-chlorobenzo[d][1,3]thiazole; (R)-2-amino-2-(naphthalen-1-yl)ethan-1-ol With N-ethyl-N,N-diisopropylamine at 130℃; for 24h; Inert atmosphere; Schlenk technique; Stage #2: With methanesulfonyl chloride; triethylamine In dichloromethane at 0 - 60℃; for 37h; Inert atmosphere; Schlenk technique;
  • 4
  • [ 2770296-89-2 ]
  • [ 110480-83-6 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetyl chloride / methanol / 1 h / -10 - 20 °C / Inert atmosphere; Schlenk technique 2: trifluoroacetic acid / dichloromethane / 1 h / 20 °C / Inert atmosphere; Schlenk technique
  • 5
  • [ CAS Unavailable ]
  • [ 110480-83-6 ]
YieldReaction ConditionsOperation in experiment
115 mg With trifluoroacetic acid In dichloromethane at 20℃; for 1h; Inert atmosphere; Schlenk technique;
  • 6
  • [ 5371-70-0 ]
  • [ 110480-83-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
In neat (no solvent) at 120℃; for 2h; Inert atmosphere;
  • 7
  • [ 110480-83-6 ]
  • [ 3087706-14-4 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: neat (no solvent) / 2 h / 120 °C / Inert atmosphere 2: potassium carbonate; palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / water; acetonitrile / 24 h / 100 °C / Inert atmosphere 3: diethylamino-sulfur trifluoride / dichloromethane; water / 8 h / -20 °C / Inert atmosphere
  • 8
  • [ 110480-83-6 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: neat (no solvent) / 2 h / 120 °C / Inert atmosphere 2: potassium carbonate; palladium diacetate; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / water; acetonitrile / 24 h / 100 °C / Inert atmosphere
 

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