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Chemical Structure| 113170-55-1 Chemical Structure| 113170-55-1

Structure of 113170-55-1

Chemical Structure| 113170-55-1

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This vitamin C derivative effectively promotes collagen synthesis and enhances osteoblast differentiation, aiding in bone repair and regeneration.

Synonyms: 2-Phospho-L-ascorbic acid magnesium; LAA2P magnesium

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Product Details of L-Ascorbic acid 2-phosphate magnesium

CAS No. :113170-55-1
Formula : C12H18Mg3O18P2
M.W : 585.12
SMILES Code : O=P(O)(OC1=C(O)[C@@]([H])([C@H](CO)O)OC1=O)O.O=P(O)(OC2=C(O)[C@@]([H])([C@H](CO)O)OC2=O)O.[Mg].[Mg].[Mg]
Synonyms :
2-Phospho-L-ascorbic acid magnesium; LAA2P magnesium
MDL No. :MFCD11045932

Safety of L-Ascorbic acid 2-phosphate magnesium

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P301+P312-P302+P352-P304+P340-P305+P351+P338

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Clinical-grade human embryonic stem cells (hESCs) 50 µg/L 6 days Used for differentiation of hESCs into hepatoblasts and ultimately hepatocyte-like cells (HLCs). Results showed that HLCs possessed typical hepatocyte morphology and characteristics of mature hepatocytes, such as metabolic-related gene expression, albumin secretion, fat accumulation, glycogen storage, and inducible cytochrome P450 activity. Cell Death Dis. 2019 Oct 10;10(10):763
porcine skin 13 mM 12 hours To study the permeability of MAP-1 and MAP-2 in porcine skin. Results showed that CO2 laser pretreatment significantly enhanced the permeability of MAP-1 and MAP-2. Molecules. 2016 Nov 16;21(11):1547
porcine cumulus-oocyte complexes (COCs) 250 μM 44 hours significantly enhanced the nuclear maturation (as indicated by higher rate of first polar body extrusion and increased Bmp15 mRNA level), reduced level of reactive oxygen species, and promoted developmental potency Sci Rep. 2018 Apr 17;8(1):6132
Umbilical cord blood hematopoietic stem and progenitor cells 150 μg/mL From day 3 of differentiation Promotes erythroid differentiation, increases the proportion of late basophilic erythroblasts, upregulates the expression of erythroid-related regulatory molecules GATA1, KLF1, ALAS2, and the globins HBG and HBB. Life Med. 2023 Nov 13;2(5):lnad043

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Mice 786-O and A498 xenograft models Intraperitoneal injection 0.5 g/kg Once daily for 6 weeks (786-O) or 4 weeks (A498) Inhibited the growth of ccRCC xenografts and significantly restored 5hmC levels EMBO Rep. 2018 Aug;19(8):e45401

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.71mL

0.34mL

0.17mL

8.55mL

1.71mL

0.85mL

17.09mL

3.42mL

1.71mL

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