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Chemical Structure| 1142952-26-8 Chemical Structure| 1142952-26-8

Structure of 1142952-26-8

Chemical Structure| 1142952-26-8

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Product Details of [ 1142952-26-8 ]

CAS No. :1142952-26-8
Formula : C6H8N2OS
M.W : 156.21
SMILES Code : O=C(N)[C@@H](N)C1=CSC=C1

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Application In Synthesis of [ 1142952-26-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1142952-26-8 ]

[ 1142952-26-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1194-87-2 ]
  • [ 1142952-26-8 ]
YieldReaction ConditionsOperation in experiment
Intermediate 5: (2S)-2-Amino-2-(3-thienyl)ethanamide; (2S)-Amino(3-thienyl)ethanoic acid (100mg) was dissolved in methanolic hydrochloric acid (1.25M, 5mL) and the solution left at room temperature for 3 days and then evaporated under a stream of nitrogen. The residue was treated with ammonium hydroxide (0.88d, 1 mL) in a sealed microwave vessel at 1000C for 10min and then cooled. Evaporation under a stream of nitrogen gave a residue which was <n="46"/>dissolved in methanol:dichloromethane (1 :1 ) and passed through a 1g aminopropyl cartridge. Evaporation of the eluent afforded impure title compound which was used without further purification.1H-NMR: (MeOD, 400 MHz) delta 7.68 (dd, 1 H), 7.54 (dd, 1 H), 7.24 (dd, 1 H)1 5.15 (s,1 H).
 

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