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Chemical Structure| 114671-83-9 Chemical Structure| 114671-83-9

Structure of 114671-83-9

Chemical Structure| 114671-83-9

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Product Details of [ 114671-83-9 ]

CAS No. :114671-83-9
Formula : C19H25IOSi
M.W : 424.39
SMILES Code : ICCCO[Si](C1=CC=CC=C1)(C(C)(C)C)C2=CC=CC=C2
MDL No. :MFCD10569613

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Application In Synthesis of [ 114671-83-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 114671-83-9 ]

[ 114671-83-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 15893-42-2 ]
  • [ 114671-83-9 ]
  • 6-((tert-butyldiphenylsilyl)oxy)-1-(4-methoxyphenyl)hexane-3-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% With manganese; FeBr2(1,2-bis(diphenylphosphino)benzene); lithium chloride; copper dichloride; In 1,2-dimethoxyethane; at 0℃; for 15h; General procedure: To alkyl iodide la~q (1.2 equiv.), acid chloride 2a (1.0 equiv.) in 1,2- dimethoxyethane (C 0.4 M) were added manganese (2.0 equiv.), copper (II) chloride (1.0 equiv.), lithium chloride (3.0 equiv.) and FeBr2(dppb) 5a (5 mol%). The reaction mixture was cooled to 0 C and stirred vigorously for 15 h at the same temperature. Upon completion of reaction, florosil was added and stirred for 30 min at 0 C and filtered through a pad of Celite, washed with ethyl acetate (10 mL) and the filtrate was dried over anhydrous Na2S04, filtered and concentrated under rotary evaporator. After concentration, purification through a basic alumina column chromatography yields the desired ketone 3 a~q
 

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