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Chemical Structure| 1148008-74-5 Chemical Structure| 1148008-74-5

Structure of 1148008-74-5

Chemical Structure| 1148008-74-5

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Product Details of [ 1148008-74-5 ]

CAS No. :1148008-74-5
Formula : C15H14BrNO
M.W : 304.18
SMILES Code : BrC1=CC=C(OCCN2CC3=CC=CC=C3)C2=C1

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Application In Synthesis of [ 1148008-74-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1148008-74-5 ]

[ 1148008-74-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 100-39-0 ]
  • [ 105655-01-4 ]
  • [ 1148008-74-5 ]
YieldReaction ConditionsOperation in experiment
95% With potassium carbonate; In N,N-dimethyl-formamide; at 20℃; b) 6-bromo-4-(phenylmethyl)-3,4-dihydro-2H-l,4-benzoxazine; A suspension of 6-bromo-3,4-dihydro-2H-l,4-benzoxazine (0.150 g, 0.70 mmol), potassium carbonate (0.242 g, 1.75 mmol), and benzyl bromide (0.179 g, 1.049 mmol) in dry DMF (1.5 mL) was stirred overnight at room temperature. The reaction was diluted with water and EtOAc and transferred to a separatory funnel. The layers were separated and the water was extracted twice with EtOAc. The combined EtOAc layers were washed with water and saturated NaCl, dried over Na2SO4, filtered and concentrated to give the title compound (0.203 g, 95%) as a slightly pink crystalline solid. MS(ES)+ m/e 305 [M+eta].
 

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