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Chemical Structure| 1149587-06-3 Chemical Structure| 1149587-06-3

Structure of 1149587-06-3

Chemical Structure| 1149587-06-3

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Product Details of [ 1149587-06-3 ]

CAS No. :1149587-06-3
Formula : C6H9N3O2
M.W : 155.16
SMILES Code : O=C(C1=CNN=C1)N(OC)C
MDL No. :MFCD14588065

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Application In Synthesis of [ 1149587-06-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1149587-06-3 ]

[ 1149587-06-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 37718-11-9 ]
  • [ 6638-79-5 ]
  • [ 1149587-06-3 ]
YieldReaction ConditionsOperation in experiment
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In N,N-dimethyl-formamide; for 24h; A N, N-dimethylformamide solution (3 mL) of 4- <n="216"/>pyrazolecarboxylic acid (150 mg, 1.34 mmol) , N,0- dimethylhydroxylamine hydrochloride (261.4 mg, 2.68 mmol), 1 -ethyl -3- (3-dimethylaminopropyl) carbodiimide, hydrochloride (513.8 mg, 2.68 mmol), 1- hydroxybenzotriazoleimidazole anhydride (54.2 mg, 0.40 mmol), and triethylamine (0.38 mL, 2.68 mmol) was stirred for 1 day. After completion of the reaction, the reaction solution was mixed with ethyl acetate and washed with saturated aqueous sodium chloride. The organic layer was dried over anhydrous sodium sulfate and evaporated under reduced pressure. The resulting crude reaction product containing the desired product was used for the next step (142.7 mg) .Morphology: colorless oil 1H-NMR(CDCl3) delta: 2.89 (s, 3H), 2.96 (s, 3H), 8.03 (s, 1H), 8.13 (s, 1H).
 

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