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Chemical Structure| 1160748-24-2 Chemical Structure| 1160748-24-2

Structure of 1160748-24-2

Chemical Structure| 1160748-24-2

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Product Details of [ 1160748-24-2 ]

CAS No. :1160748-24-2
Formula : C9H10N4O2
M.W : 206.20
SMILES Code : COC1=CC=CC(NC(CN=[N+]=[N-])=O)=C1

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Application In Synthesis of [ 1160748-24-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1160748-24-2 ]

[ 1160748-24-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 17641-08-6 ]
  • [ 1160748-24-2 ]
YieldReaction ConditionsOperation in experiment
With sodium azide; In water; N,N-dimethyl-formamide; at 100℃; for 6h; General procedure: The freshly synthesized above intermediates were heated at 100 C with sodium azide (0.1mol) in DMF-H2O for 6 h. The progress of the reaction was monitored by TLC using ethylacetate: hexane (1:9) as a solvent system. The reaction mixture was poured on crushed ice.Ethyl acetate was added to the mixture and the organic layer was separated. The organiclayers were dried over MgSO4 and solvent was removed under reduced pressure. All theazides (2a-r) were synthesized from respective amines, were obtained as solid compoundsexcept azide (2e) obtained from o-anisidine in liquid state. This azide (2e) was extracted inorganic layer using ethyl acetate and solvent is removed under reduced pressure. After this itwas used for further reaction without any purification. All the newly synthesized solid azideswere crystallised in ethanol and then used for further reaction.[
 

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