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Chemical Structure| 1175525-90-2 Chemical Structure| 1175525-90-2

Structure of 1175525-90-2

Chemical Structure| 1175525-90-2

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Product Details of [ 1175525-90-2 ]

CAS No. :1175525-90-2
Formula : C9H11BrIN
M.W : 340.00
SMILES Code : CCNCC1=CC(Br)=CC=C1I
MDL No. :MFCD13249545

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Application In Synthesis of [ 1175525-90-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1175525-90-2 ]

[ 1175525-90-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 689291-89-2 ]
  • [ 75-04-7 ]
  • [ 1175525-90-2 ]
YieldReaction ConditionsOperation in experiment
Step 2: (5-Bromo-2-iodo-benzyl)-ethyl-amine To 5-bromo-2-iodo-benzaldehyde (5.0 g, 16.1 mmol) in MeOH (20 mL) was added ethylamine (2M in MeOH; 16 mL, 24.0 mmol), followed by acetic acid (1.0 mL, 17.8 mmol), and the mixture was stirred at room temperature for 30 minutes. Sodium cyanoborohydride (2.0 g, 31.8 mmol) was then added over 5 minutes, and the reaction was stirred at room temperature over the weekend. The mixture was concentrated and partitioned between EtOAc and saturated aqueous NaHCO3. The aqueous layer was extracted with EtOAc, and the combined organic layers were dried over MgSO4, filtered, and concentrated. The residue was purified by silica gel chromatography (0-5% MeOH in CH2Cl2) to give the title compound.
  • 2
  • [ 121554-10-7 ]
  • [ 1175525-90-2 ]
 

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