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Chemical Structure| 1177423-60-7 Chemical Structure| 1177423-60-7

Structure of 1177423-60-7

Chemical Structure| 1177423-60-7

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Product Details of [ 1177423-60-7 ]

CAS No. :1177423-60-7
Formula : C4H6N4OS
M.W : 158.18
SMILES Code : O=C(C1=NN=C(N)S1)NC
MDL No. :MFCD23949052

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Application In Synthesis of [ 1177423-60-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1177423-60-7 ]

[ 1177423-60-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 64837-53-2 ]
  • [ 74-89-5 ]
  • [ 1177423-60-7 ]
YieldReaction ConditionsOperation in experiment
In methanol; ethanol; at 20 - 70℃; To a suspension of ethyl 5-amino-l,3,4-thiadiazole-2-carboxylate (106 mg, 0.612 mmol) in methanol (1.5 mL) was added 33 wt percent ethanol solution of <n="108"/>methylamine (0.5 mL, 4.00 mmol). The mixture was stirred at room temperature for 6 h, heated to 70 0C and cooled. The mixture was concentrated, mixed with water and lyophilized to give 5-amino-N-methyl-l,3,4-thiadiazole-2-carboxamide as a white solid (99 mg). 1H NMR (400 MHz, DMSO-d6) delta ppm 8.69 (q, J=4.8 Hz, 1 H), 7.70 (s, 2 H) 2.73 (d, J=4.78 Hz, 3 H); MS (ES+) m/z: 159 (M+H); LC retention time: 0.44 min (analytical HPLC Method A).
 

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