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Chemical Structure| 1192122-31-8 Chemical Structure| 1192122-31-8

Structure of 1192122-31-8

Chemical Structure| 1192122-31-8

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Product Details of [ 1192122-31-8 ]

CAS No. :1192122-31-8
Formula : C19H28N2O3
M.W : 332.44
SMILES Code : O=C(N1CCC(N2CCC(OC)CC2)CC1)OCC3=CC=CC=C3
MDL No. :N/A

Safety of [ 1192122-31-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1192122-31-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1192122-31-8 ]

[ 1192122-31-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 19099-93-5 ]
  • [ 4045-25-4 ]
  • [ 1192122-31-8 ]
YieldReaction ConditionsOperation in experiment
To a solution of <strong>[4045-25-4]4-methoxypiperidine hydrochloride</strong> QSl.1 mg) in a MeOH - THF mixed solvent (1/2, 6 mL) were added benzyl 4-oxo-l-piperazinecarboxylate (549.6 mg) and acetic acid (0.1 mL) at room temperature. The mixture was warmed to 45 Deg for 30 Min.To the mixture was slowly added sodium triacetoxyborohydride (1.65 g) for 4.5 hrs. After 2 hrs stirring, the reaction was quenched by addition of l.OM aqueous sodium hydroxyde (the <n="86"/>pH was adjusted to 9), then extracted with AcOEt (x 3). The combined organic layer was washed with water and brine, dried over magnesium sulfate, then concentrated. The residual dark red oil was purified by amine-capped silica gel column chromatography (hexane / AcOEt = 90/10 to 80/20) to give benzyl 4-methoxy-l,4'-birhoiperidine-l'-carboxylate (137 mg).
 

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