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Chemical Structure| 1193687-88-5 Chemical Structure| 1193687-88-5

Structure of 1193687-88-5

Chemical Structure| 1193687-88-5

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Product Details of [ 1193687-88-5 ]

CAS No. :1193687-88-5
Formula : C20H23FN4O6
M.W : 434.42
SMILES Code : O=C(OCC)C(NC(C)(C1=NC(C(NCC2=CC=C(F)C=C2)=O)=C(O)C(N1C)=O)C)=O

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Application In Synthesis of [ 1193687-88-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1193687-88-5 ]

[ 1193687-88-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 518048-03-8 ]
  • [ 4755-77-5 ]
  • [ 1193687-88-5 ]
YieldReaction ConditionsOperation in experiment
25 mg With triethylamine; In chloroform; at 0 - 20℃; for 2.5h; In a clean and dry 3000 mL round bottom flask, it was taken 400 mL of chloroform, 40 g of compound 8 and 38 g of triethylamine at room temperature under gentle stirring, then added 32 g of ethyl oxalyl chloride dropwise over a period of 0.5 h at 0-5 C. The reaction mass was maintained for 1 h at 0-5 C and another 1 h at room temperature until the reaction get complies in TLC. After completion of the reaction added 1N HCl (200 mL) to the wine red colour reaction mass to remove excess of triethylamine, the obtained organic residue after distillation under reduced pressure was isolated in isopropyl ether (IPE) and got 25 g pure material. 1H NMR (DMSO-d6): delta 12.21 (s, 1H),9.48 (s, 1H), 9.06 (t, 1H), 7.38 (t, 2H), 7.16 (t, 2H), 4.51 (d, 2H),3.36 (s, 3H), 1.64 (s, 6H); 13C NMR (DMSO-d6): delta 168.45, 162.53, 160.52, 160.12, 158.59, 156.92, 151.74, 145.72, 134.90,134.88, 129.47, 124.40, 115.25, 115.04, 62.19, 57.16, 41.65,32.96, 26.90, 13.78. Mass: M+: 434.42, M-H: 433.3 (-ve scan).
 

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