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Chemical Structure| 263399-35-5 Chemical Structure| 263399-35-5

Structure of 12,13-DiHOME
CAS No.: 263399-35-5

Chemical Structure| 263399-35-5

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Synonyms: (±)12(13)-DiHOME; Isoleukotoxin diol

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Product Details of 12,13-DiHOME

CAS No. :263399-35-5
Formula : C18H34O4
M.W : 314.46
SMILES Code : CCCCC[C@@H](O)[C@@H](O)C/C=C\CCCCCCCC(O)=O
Synonyms :
(±)12(13)-DiHOME; Isoleukotoxin diol
MDL No. :MFCD12912337

Safety of 12,13-DiHOME

Isoform Comparison

Biological Activity

In Vivo:

Species
Animal Model
Administration Dosage Frequency Description References
Mice ApoE−/− mice Drinking water 10ug/kg body weight Continued for three months 12,13-diHOME feeding reduced lipid deposition and macrophage accumulation in the aortic roots and descending aorta of HFD-ApoE?/? mice, improved endothelial function, and decreased the severity of atherosclerosis PMC9308716

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.18mL

0.64mL

0.32mL

15.90mL

3.18mL

1.59mL

31.80mL

6.36mL

3.18mL

 

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