Home Cart 0 Sign in  

[ CAS No. 1202-66-0 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1202-66-0
Chemical Structure| 1202-66-0
Structure of 1202-66-0 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 1202-66-0 ]

Related Doc. of [ 1202-66-0 ]

Alternatived Products of [ 1202-66-0 ]

Product Details of [ 1202-66-0 ]

CAS No. :1202-66-0 MDL No. :MFCD01670887
Formula : C10H13NO2 Boiling Point : -
Linear Structure Formula :- InChI Key :ATDWJOOPFDQZNK-UHFFFAOYSA-N
M.W : 179.22 Pubchem ID :121051
Synonyms :

Safety of [ 1202-66-0 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P305+P351+P338 UN#:N/A
Hazard Statements:H319 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1202-66-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 1202-66-0 ]
  • Downstream synthetic route of [ 1202-66-0 ]

[ 1202-66-0 ] Synthesis Path-Upstream   1~17

  • 1
  • [ 60-19-5 ]
  • [ 108-24-7 ]
  • [ 1202-66-0 ]
Reference: [1] Journal of the American Chemical Society, 2009, vol. 131, # 36, p. 13132 - 13141
[2] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 1, p. 478 - 487
[3] Archives of Biochemistry, 1959, vol. 83, p. 76,77
  • 2
  • [ 51-67-2 ]
  • [ 108-24-7 ]
  • [ 1202-66-0 ]
YieldReaction ConditionsOperation in experiment
86% With sodium hydrogencarbonate In tetrahydrofuran; water GK3-015 was prepared according to the following reaction scheme 12
Reference: [1] Patent: US9522908, 2016, B2, . Location in patent: Page/Page column 57
[2] Biochemical Pharmacology, 1998, vol. 55, # 1, p. 37 - 43
[3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2014, vol. 53, # 1, p. 83 - 89
  • 3
  • [ 51-67-2 ]
  • [ 141-78-6 ]
  • [ 1202-66-0 ]
YieldReaction ConditionsOperation in experiment
99% at 90℃; for 24 h; Inert atmosphere General procedure: To a solution of tBuCO2H (3d) (30.9 mg, 0.30 mmol) in EtOAc (3.0 mL) at room rtemperature was added 3-amino-1-phenylbutane (1) (48.7 μL, 0.30 mmol). The reaction mixture was refluxed (90 °C) for 24 h and then it was evaporated the solvent. The crude product was purified preparative thin layer chromatography on silica (hexane/EtOAc/35percent NH3 = 25/75/1) to afford the corresponding acetoamide 2 (57.0 mg, 99percent yield) as a colorless oil.
Reference: [1] Tetrahedron Letters, 2017, vol. 58, # 12, p. 1181 - 1184
  • 4
  • [ 14383-56-3 ]
  • [ 1202-66-0 ]
Reference: [1] Patent: US6352993, 2002, B1, . Location in patent: Page column 11
  • 5
  • [ 51-67-2 ]
  • [ 75-36-5 ]
  • [ 1202-66-0 ]
Reference: [1] Journal of Antibiotics, 2001, vol. 54, # 10, p. 827 - 830
  • 6
  • [ 51-67-2 ]
  • [ 1694-31-1 ]
  • [ 1202-66-0 ]
Reference: [1] European Journal of Organic Chemistry, 2017, vol. 2017, # 11, p. 1526 - 1539
  • 7
  • [ 51-67-2 ]
  • [ 64-19-7 ]
  • [ 1202-66-0 ]
Reference: [1] Tetrahedron, 1983, vol. 39, # 20, p. 3253 - 3260
[2] Journal of Natural Products, 2006, vol. 69, # 10, p. 1379 - 1383
  • 8
  • [ 72131-33-0 ]
  • [ 1202-66-0 ]
Reference: [1] Patent: US4258058, 1981, A,
  • 9
  • [ 51-67-2 ]
  • [ 1202-66-0 ]
Reference: [1] European Journal of Organic Chemistry, 2017, vol. 2017, # 11, p. 1526 - 1539
  • 10
  • [ 51-67-2 ]
  • [ 60759-49-1 ]
  • [ 1202-66-0 ]
Reference: [1] Tetrahedron Letters, 1981, vol. 22, # 13, p. 1257 - 1258
[2] Tetrahedron, 1983, vol. 39, # 20, p. 3253 - 3260
  • 11
  • [ 58484-75-6 ]
  • [ 1202-66-0 ]
  • [ 161644-20-8 ]
Reference: [1] Chemistry Letters, 1998, # 2, p. 111 - 112
[2] Bulletin of the Chemical Society of Japan, 1997, vol. 70, # 5, p. 965 - 975
  • 12
  • [ 51-67-2 ]
  • [ 75-36-5 ]
  • [ 1202-66-0 ]
  • [ 14383-56-3 ]
  • [ 20284-85-9 ]
Reference: [1] Tetrahedron, 2009, vol. 65, # 8, p. 1618 - 1629
  • 13
  • [ 51-67-2 ]
  • [ 128459-09-6 ]
  • [ 1202-66-0 ]
Reference: [1] Tetrahedron Letters, 1990, vol. 31, # 2, p. 243 - 246
  • 14
  • [ 51-67-2 ]
  • [ 75178-12-0 ]
  • [ 1202-66-0 ]
  • [ 101001-90-5 ]
Reference: [1] Chemistry Letters, 1980, p. 563 - 566
  • 15
  • [ 58484-75-6 ]
  • [ 613-21-8 ]
  • [ 1202-66-0 ]
  • [ 161644-20-8 ]
Reference: [1] Chemistry Letters, 1998, # 2, p. 111 - 112
  • 16
  • [ 64318-28-1 ]
  • [ 1202-66-0 ]
Reference: [1] Patent: US9522908, 2016, B2,
  • 17
  • [ 51-67-2 ]
  • [ 72-89-9 ]
  • [ 1202-66-0 ]
Reference: [1] Biochemistry, 2014, vol. 53, # 49, p. 7777 - 7793
Same Skeleton Products
Historical Records

Related Functional Groups of
[ 1202-66-0 ]

Aryls

Chemical Structure| 103188-46-1

[ 103188-46-1 ]

(E)-N-(3,4-Dihydroxyphenethyl)-3-(4-hydroxyphenyl)acrylamide

Similarity: 0.86

Chemical Structure| 80311-94-0

[ 80311-94-0 ]

N-(2-Hydroxybenzyl)acetamide

Similarity: 0.83

Chemical Structure| 207989-87-5

[ 207989-87-5 ]

5-(4-Hydroxyphenyl)pyrrolidin-2-one

Similarity: 0.80

Chemical Structure| 23128-74-7

[ 23128-74-7 ]

N,N'-(Hexane-1,6-diyl)bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanamide)

Similarity: 0.76

Chemical Structure| 501-13-3

[ 501-13-3 ]

N-(4-Aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide

Similarity: 0.76

Amides

Chemical Structure| 103188-46-1

[ 103188-46-1 ]

(E)-N-(3,4-Dihydroxyphenethyl)-3-(4-hydroxyphenyl)acrylamide

Similarity: 0.86

Chemical Structure| 80311-94-0

[ 80311-94-0 ]

N-(2-Hydroxybenzyl)acetamide

Similarity: 0.83

Chemical Structure| 22245-98-3

[ 22245-98-3 ]

6-Hydroxy-3,4-dihydroisoquinolin-1(2H)-one

Similarity: 0.80

Chemical Structure| 207989-87-5

[ 207989-87-5 ]

5-(4-Hydroxyphenyl)pyrrolidin-2-one

Similarity: 0.80

Chemical Structure| 22246-05-5

[ 22246-05-5 ]

7-Hydroxy-3,4-dihydro-2H-isoquinolin-1-one

Similarity: 0.80

Amines

Chemical Structure| 103188-46-1

[ 103188-46-1 ]

(E)-N-(3,4-Dihydroxyphenethyl)-3-(4-hydroxyphenyl)acrylamide

Similarity: 0.86

Chemical Structure| 80311-94-0

[ 80311-94-0 ]

N-(2-Hydroxybenzyl)acetamide

Similarity: 0.83

Chemical Structure| 23128-74-7

[ 23128-74-7 ]

N,N'-(Hexane-1,6-diyl)bis(3-(3,5-di-tert-butyl-4-hydroxyphenyl)propanamide)

Similarity: 0.76

Chemical Structure| 501-13-3

[ 501-13-3 ]

N-(4-Aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide

Similarity: 0.76

Chemical Structure| 17061-63-1

[ 17061-63-1 ]

N-(4-Methoxybenzyl)formamide

Similarity: 0.76