[ CAS No. 1204-79-1 ]

Name: 1204-79-1|4'-Amino-[1,1'-biphenyl]-4-ol|98%
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Quality Control of [ 1204-79-1 ]

COA NMR CNMR HPLC LC-MS

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Alternatived Products of [ 1204-79-1 ]

Product Details of [ 1204-79-1 ]

CAS No. :	1204-79-1	MDL No. :	MFCD00463439
Formula :	C₁₂H₁₁NO	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	LQZZZAFQKXTFKH-UHFFFAOYSA-N
M.W :	185.22 g/mol	Pubchem ID :	14565
Synonyms :

Safety of [ 1204-79-1 ]

Signal Word:	Warning	Class:
Precautionary Statements:	P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501	UN#:
Hazard Statements:	H302-H312-H315-H319-H332-H335	Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1204-79-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 1204-79-1 ]

[ 1204-79-1 ] Synthesis Path-Downstream 1~59

1
[ 110-86-1 ]
[ 1204-79-1 ]
[ 98-88-4 ]
[ 404852-41-1 ]

Reference： [1]Journal of the Chemical Society,1926,p. 2712

2
[ 98-01-1 ]
[ 1204-79-1 ]
[ 101600-68-4 ]

Reference： [1]Doklady Akademii Nauk SSSR,1957,vol. 114,p. 116
Doklady Chemistry, 112-117 <1957> 461,

3
[ 85-44-9 ]
[ 1204-79-1 ]
[ 111499-73-1 ]

Reference： [1]Patent: DE887501,1950,C

4
[ 1204-79-1 ]
[ 92-88-6 ]

Reference： [1]Justus Liebigs Annalen der Chemie,1912,vol. 390,p. 175
Chemische Berichte,1907,vol. 40,p. 1903

5
[ 1204-79-1 ]
[ 29558-78-9 ]

Reference： [1]Gazzetta Chimica Italiana,1928,vol. 58,p. 634

6
[ 1204-79-1 ]
[ 15599-12-9 ]

Reference： [1]Justus Liebigs Annalen der Chemie,1912,vol. 390,p. 175
Chemische Berichte,1907,vol. 40,p. 1903

7
[ 100872-66-0 ]
[ 1204-79-1 ]

Reference： [1]Chemische Berichte,1906,vol. 39,p. 4181

8
[ 1204-79-1 ]
[ 108-24-7 ]
[ 47082-07-5 ]

Reference： [1]Journal of the American Chemical Society,1926,vol. 48,p. 487
[2]Journal of the Chemical Society,1926,p. 2712

9
[ 1204-79-1 ]
[ 108-24-7 ]
[ 47082-07-5 ]
4-Acetoxy-4'-diacetylamino-biphenyl [ No CAS ]

Reference： [1]Chemische Berichte,1926,vol. 59,p. 2176
[2]Chemische Berichte,1926,vol. 59,p. 2176

10
[ 1204-79-1 ]
[ 100-52-7 ]
[ 101895-11-8 ]

Reference： [1]Journal of the Chemical Society,1926,p. 2712
[2]Chemische Berichte,1926,vol. 59,p. 2176

11
[ 1204-79-1 ]
[ 98-88-4 ]
[ 404852-41-1 ]

Reference： [1]Journal of the Chemical Society,1926,p. 2712

12
[ 1204-79-1 ]
[ 98-88-4 ]
4-Benzoylamino-4'-benzoyloxy-biphenyl [ No CAS ]

Reference： [1]Journal of the American Chemical Society,1926,vol. 48,p. 487

13
[ 1204-79-1 ]
[ 64-19-7 ]
[ 13171-43-2 ]

Reference： [1]Patent: DE85988,1800,C
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167

14
[ 100-65-2 ]
[ 108-95-2 ]
[ 1204-79-1 ]

Reference： [1]Chemische Berichte,1901,vol. 34,p. 62,64

15
[ 1227476-15-4 ]
[ 108-95-2 ]
[ 1204-79-1 ]

Reference： [1]Chemische Berichte,1926,vol. 59,p. 2176

16
[ 1204-79-1 ]
[ 57-06-7 ]
[ 101279-98-5 ]

Reference： [1]Doklady Akademii Nauk SSSR,1957,vol. 114,p. 116,118
Doklady Chemistry, 112-117<1957>461,

17
[ 3916-44-7 ]
[ 1204-79-1 ]

Reference： [1]Chemistry - A European Journal,2008,vol. 14,p. 987 - 995
[2]Journal of the American Chemical Society,2003,vol. 125,p. 15395 - 15401
[3]Mutation Research - Genetic Toxicology,1994,vol. 320,p. 45 - 58

18
[ 7664-93-9 ]
[ 100-65-2 ]
[ 1204-79-1 ]

Reference： [1]Justus Liebigs Annalen der Chemie,1912,vol. 390,p. 175
Chemische Berichte,1907,vol. 40,p. 1903

19
[ 7647-01-0 ]
(E)-3-Ureido-but-2-enoic acid ethyl ester [ No CAS ]
[ 17082-12-1 ]
[ 108-95-2 ]
[ 1204-79-1 ]

Reference： [1]Chemische Berichte,1926,vol. 59,p. 2176

20
[ 7664-93-9 ]
[ 100-65-2 ]
[ 108-95-2 ]
[ 1204-79-1 ]
[ 21849-92-3 ]
[ 123-30-8 ]
[ 62-53-3 ]

Reference： [1]Justus Liebigs Annalen der Chemie,1912,vol. 390,p. 175
Chemische Berichte,1907,vol. 40,p. 1903

23
4-amino-diphenyldiazonium chloride-(4') [ No CAS ]
[ 1204-79-1 ]

Reference： [1]Patent: DE51576,
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 2,p. 469
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 2,p. 469
[2]Patent: DE52661,
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 2,p. 470
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 2,p. 470

24
[ 100-65-2 ]
phenol (5 mol) [ No CAS ]
[ 1204-79-1 ]

Reference： [1]Justus Liebigs Annalen der Chemie,1912,vol. 390,p. 175
Chemische Berichte,1907,vol. 40,p. 1903

25
[ 1204-79-1 ]
chloro water [ No CAS ]
6-chloroimino-[3,3']bicyclohexa-1,4-dienyliden-6-one [ No CAS ]

Reference： [1]Roczniki Chemii,vol. 5,p. 347
Chemisches Zentralblatt,1926,vol. 97,p. 2881

26
[ 7647-01-0 ]
[ 1204-79-1 ]
sodium hypochlorite [ No CAS ]
6-chloroimino-[3,3']bicyclohexa-1,4-dienyliden-6-one [ No CAS ]

Reference： [1]Justus Liebigs Annalen der Chemie,1908,vol. 363,p. 322

27
[ 7664-93-9 ]
(4'-hydroxy-biphenyl-4-yl)-oxalamic acid [ No CAS ]
[ 1204-79-1 ]

Reference： [1]Chemische Berichte,1906,vol. 39,p. 4181

28
[ 1204-79-1 ]
[ 3007-72-5 ]
4'-[4-(n-nonylamino)phenylazo]biphenyl-4-ol [ No CAS ]

Reference： [1]Russian Chemical Bulletin,2001,vol. 50,p. 1248 - 1254

29
[ 1204-79-1 ]
[ 130296-37-6 ]
N-(1-hexylheptyl)-N'-(4-(4'-hydroxybiphenyl))-perylene-3,4:9,10-tetracarboxylic bisimide [ No CAS ]

Reference： [1]Chemistry - A European Journal,2002,vol. 8,p. 5630 - 5643

30
[ 1204-79-1 ]
[ 75-36-5 ]
[ 13171-43-2 ]

Reference： [1]Journal of the American Chemical Society,2003,vol. 125,p. 15395 - 15401

31
[ 1204-79-1 ]
(S)-2-chloro-3-methylbutyric acid 4'-[4-(n-nonylamino)phenylazo]biphenyl-4-yl ester [ No CAS ]

Reference： [1]Russian Chemical Bulletin,2001,vol. 50,p. 1248 - 1254

32
[ 1211-40-1 ]
[ 1204-79-1 ]

Reference： [1]Mutation Research - Genetic Toxicology,1994,vol. 320,p. 45 - 58

33
[ 1204-79-1 ]
[ 6792-99-0 ]

Reference： [1]Patent: DE85988,1800,C
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167
[2]Patent: DE85988,1800,C
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167
    Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167

34
[ 1204-79-1 ]
[ 13171-43-2 ]

Reference： [1]Journal of the American Chemical Society,1926,vol. 48,p. 487

35
[ 1204-79-1 ]
[ 2221-22-9 ]

Reference： [1]Patent: DE85988,1800,C
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167
Fortschr. Teerfarbenfabr. Verw. Industriezweige,vol. 4,p. 1167

36
[ 1204-79-1 ]
[ 404852-41-1 ]

Reference： [1]Journal of the American Chemical Society,1926,vol. 48,p. 487
[2]Journal of the Chemical Society,1926,p. 2712

37
[ 1204-79-1 ]
4-Acetylamino-4'-benzoyloxy-biphenyl [ No CAS ]

Reference： [1]Journal of the American Chemical Society,1926,vol. 48,p. 487

38
[ 1204-79-1 ]
4-Acetoxy-4'-benzoylamino-biphenyl [ No CAS ]

Reference： [1]Journal of the American Chemical Society,1926,vol. 48,p. 487

39
[ 1204-79-1 ]
[ 860604-68-8 ]

Reference： [1]Journal of the Chemical Society,1926,p. 2712

40
[ 24424-99-5 ]
[ 1204-79-1 ]
[ 848853-75-8 ]

Yield	Reaction Conditions	Operation in experiment
41.1%	With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 - 23℃; for 16h;Inert atmosphere;	Di-tert-butyl dicarbonate (0.860 g, 3.94 mmol) was added to 4'-amino-[l,l'-biphenyl]-4-ol (0.73 g, 3.94 mmol), DIEA (2.065 mL, 11.82 mmol) in DMF (10 mL) at 0Cunder nitrogen. The resulting mixture was stirred at rt for 16 h. The reaction mixture was concentrated and diluted with DCM (50 mL) then washed sequentially with water (3 x 50 mL) and saturated brine (50 mL). The organic layer was dried over Na2S0 , filtered and evaporated to afford crude product. The crude product was purified by flash silica chromatography, elution gradient 0 to 20% MeOH in DCM. Pure fractions were evaporated to dryness to afford tert-butyl (4'-hydroxy-[l,l'-biphenyl]-4- yl)carbamate (0.462 g, 41.1 %) as a yellow solid. NMR (300 MHz, DMSO) d 1.46 (s, 9H), 6.74 - 6.83 (m, 2H), 7.36 - 7.51 (m, 6H), 9.35 (s, 1H), 9.44 (s, 1H). ES+m/z [M-tBu]+: 230, HPLC tR= 1.33 min (97.0%).
	In DMF (N,N-dimethyl-formamide); at 20℃;	[0167] Example 15: Synthesis OF 4 -(2-METHOXY-2-OXOETHOXY)-1, 1 -BIPHENYL-4- aminium chloride. [0168] Step 1: (4 -HYDROXY-BIPHENYL-4-YL)-CARBAMIC acid ter-butyl ester. Triethylamine (786 PAL, 5.64 mmol) and DI-TE7T-BUTYL dicarbonate were added to a solution of 4'- amino-biphenyl-4-ol (0.5 g, 1.88 mmol), prepared in step 4 of Example 13, in DMF. After the addition the reaction stirred at room temperature overnight. The solvent was removed under reduced pressure and the residue partitioned between water and ethyl acetate. The aqueous layer was separated and extracted multiple times with ethyl acetate. The combined extracts were washed with brine, dried (NA2S04) and the solvent removed under reduced pressure to give (4'- hydroxy-biphenyl-4-yl) -carbamic acid tert-butyl ester. The material was used in subsequent reactions without purification.

Reference： [1]Patent: WO2021/180952,2021,A1 .Location in patent: Page/Page column 40; 42-43
[2]Patent: WO2005/30702,2005,A1 .Location in patent: Page/Page column 62-63

41
[ 1204-79-1 ]
[ 7778-42-9 ]
[ 319015-80-0 ]

Yield	Reaction Conditions	Operation in experiment
	With sodium chloride; In tetrahydrofuran; chloroform; N,N-dimethyl acetamide;	Example 96 43 mg of 4'-aminobiphenyl-4-ol was dissolved in 0.7 ml of N,N-dimethylacetamide, and 107 mg of sulfamoyl chloride was added thereto under cooling with ice, followed by stirring at room temperature for 2.4 hours. After the reaction mixture was poured into a saturated aqueous solution of sodium chloride, the product was extracted with ethyl acetate. The organic layer was washed with water and dried over anhydrous magnesium sulfate. After the solvent was distilled off, the resulting crude product was purified by TLC (using a 17:10 mixture of chloroform and tetrahydrofuran as the developing solvent) to obtain 42 mg of 4'-(sulfamoylamino)biphenyl-4-yl sulfamate. 1H-NMR(CD3OD, δ): 7.30(2H, d, J=8.7Hz), 7.37(2H, d, J=8.7Hz), 7.56(2H, d, J=8.7Hz), 7.63(2H, d, J=8.7Hz). MS(m/z): 343(M+), 264, 184.

Reference： [1]Patent: EP1193250,2002,A1

42
[ 1204-79-1 ]
[ 18162-48-6 ]
[ 1032620-87-3 ]

Reference： [1]Chemistry - A European Journal,2008,vol. 14,p. 987 - 995

43
[ 106-41-2 ]
[ 89415-43-0 ]
[ 1204-79-1 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,p. 824 - 828

44
[ 1204-79-1 ]
[ 1357144-86-5 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,p. 824 - 828

45
[ 1204-79-1 ]
C₂₉H₂₇NO₄ [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,p. 824 - 828

46
[ 1204-79-1 ]
[ 2243-83-6 ]
[ 1357144-99-0 ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2012,vol. 22,p. 824 - 828

47
[ 20947-47-1 ]
[ 1204-79-1 ]
[ 1392445-14-5 ]
[ 1392445-09-8 ]

Yield	Reaction Conditions	Operation in experiment
11%; 78%	In dichloromethane; at 20℃; for 0.0833333h;	General procedure: 7-Bromo-2-methylquinoline-5,8-dione (5) or 7-bromoquinoline-5,8-dione (6) (19.92 mmol, 1 equiv) was dissolved in dichloromethane (30 mL) and amine (59.78, 3 equiv) was added. After stirring for 5 min at rt, H2O (50 mL) was added into the mixture and extracted with dichloromethane, dried by Na2SO4 and concentrated in vacuo. The residue was puried by ash column chromatography (EtOAc/n-hexane 40:60 to 50:50) to give 7a-e, 8a-e, 9a-e, and 10a-e.

Reference： [1]European Journal of Medicinal Chemistry,2012,vol. 54,p. 936 - 942

48
[ 180208-53-1 ]
[ 1204-79-1 ]
[ 1392445-04-3 ]
[ 1392444-96-0 ]

Yield	Reaction Conditions	Operation in experiment
11%; 76%	In dichloromethane; at 20℃; for 0.0833333h;	General procedure: 7-Bromo-2-methylquinoline-5,8-dione (5) or 7-bromoquinoline-5,8-dione (6) (19.92 mmol, 1 equiv) was dissolved in dichloromethane (30 mL) and amine (59.78, 3 equiv) was added. After stirring for 5 min at rt, H2O (50 mL) was added into the mixture and extracted with dichloromethane, dried by Na2SO4 and concentrated in vacuo. The residue was puried by ash column chromatography (EtOAc/n-hexane 40:60 to 50:50) to give 7a-e, 8a-e, 9a-e, and 10a-e.

Reference： [1]European Journal of Medicinal Chemistry,2012,vol. 54,p. 936 - 942

49
[ 83-72-7 ]
[ 1204-79-1 ]
[ 1392444-99-3 ]

Yield	Reaction Conditions	Operation in experiment
72%	In ethanol; dichloromethane; for 1h;Reflux;	General procedure: A solution of 2-hydroxynapthoquinone (12) (1 equiv) in 5 mL of dichloromethane was added dropwise to a solution of appropriate amine (3 equiv) in 15 mL of EtOH. The reaction was refluxed for 1 h. After concentration in vacuo, the residue was directly puried by ash column chromatography (EtOAc/n-hexane 40:60 to 50:50) to give 13-15.

Reference： [1]European Journal of Medicinal Chemistry,2012,vol. 54,p. 936 - 942

50
[ 1083313-80-7 ]
[ 1204-79-1 ]
N-(4'-hydroxy-[1,1'-biphenyl]-4-yl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
62%	With pyridine; In dichloromethane; for 12h;	N-(4'-hydroxy-[1,1'-biphenyl]-4-yl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide (54) A solution of acid chloride (5b, 0.27 mmol), in anhydrous dichloromethane (2 mL) was added to a solution of the aniline (53, 0.18 mmol) and anhydrous pyridine (0.94 mmol) in anhydrous dichloromethane (5 mL). After 12 h, the solvent was removed and the residue purified via column chromatography (SiO2, 10:1, DCM: methanol) to afford 54 as a off-white amorphous solid (62%). 1H NMR (500 MHz, DMSO-d6) δ 9.50 (s, 1H, NH), 8.02 (dd, J = 8.6, 2.4 Hz, 1H), 7.98 (d, J = 2.4 Hz, 1H), 7.82 (d, J = 8.7 Hz, 2H), 7.56 (d, J = 8.7 Hz, 2H), 7.49 (d, J = 8.6 Hz, 2H), 7.37 (t, J = 7.9 Hz, 1H), 7.25 (d, J = 8.7 Hz, 1H), 7.15- 7.07 (m, 2H), 6.95 (ddd, J = 8.3, 2.6, 1.0 Hz, 1H), 6.84 (d, J = 8.6 Hz, 2H), 3.86 (s, 3H), 3.80 (s, 3H). 13C NMR (126 MHz, DMSO) δ 164.61, 158.93, 158.66, 156.75, 138.82, 137.79, 135.24, 130.51, 129.79, 129.19, 129.11, 129.06, 127.29, 126.91, 125.89, 121.74, 120.63, 115.64, 115.16, 112.53, 111.39, 55.83, 55.07. HRMS (ESI+) m/z [M+Na+] calcd for C27H23NO4Na 448.1525; found 448.1522.

Reference： [1]Patent: WO2015/70091,2015,A1 .Location in patent: Page/Page column 145

51
[ 1204-79-1 ]
3',6-dimethoxy-N-(4'-(2-(piperidin-2-yl)ethoxy)-[1,1'-biphenyl]-4-yl)-[1,1'-biphenyl]-3-carboxamide [ No CAS ]

Reference： [1]Patent: WO2015/70091,2015,A1

52
[ 1204-79-1 ]
3',6-dimethoxy-N-(4'-(((1R,3s,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)oxy)-[1,1'-biphenyl]-4-yl)-[1,1'-biphenyl]-3-carboxamide [ No CAS ]

Reference： [1]Patent: WO2015/70091,2015,A1

53
[ 1204-79-1 ]
N-(4'-(3-(dimethylamino)propoxy)-[1,1'-biphenyl]-4-yl)-3',6-dimethoxy-[1,1'-biphenyl]-3-carboxamide [ No CAS ]

Reference： [1]Patent: WO2015/70091,2015,A1

54
[ 1204-79-1 ]
[ 90-02-8 ]
4'-((2-hydroxybenzyl)amino)-[1,1'-biphenyl]-4-ol [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
		General procedure: Under an atmosphere of N2, 0.175 g (1 mmol) compd. 2 was dissolved in methanol, 0.11 mL (1.05 mmol) salicylaldehyde was added and stirred overnight at room temperature. When compd. 2 disappeared, NaBH4 (61 mg, 1.6 mmol) was added. After stirring for 10 min, the reaction was quenched by sat. NH4Cl solution, then extracted with CH2Cl2 (3×20 mL), and the organic layer was washed with saturated NaCl aqueous solution, dried over anhydrous Na2SO4 and purified by flash chromatography (PE:EtOAc = 15:1) to afford 0.230 g (82%) E6 as white solid.

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2015,vol. 25,p. 3057 - 3061

55
[ 71597-85-8 ]
[ 540-37-4 ]
[ 1204-79-1 ]

Yield	Reaction Conditions	Operation in experiment
	With bis-triphenylphosphine-palladium(II) chloride; sodium carbonate; In 1,4-dioxane; water;Inert atmosphere; Reflux;	General procedure: To 0.329 g (1.5 mmol) 4-iodoaniline, 1.8 mmol ArB(OH)2, 0.318 g (3 mmol) Na2CO3 and 75 mg (0.075 mmol) PdCl2(PPh3)2, 15 mL of a blended solution of dioxane and water (v/v = 3/1) was added under N2 atmosphere. Then the reaction was heated to reflux and monitored by TLC. Upon cooling, the reaction mixture was dilute with sat. NH4Cl solution, then extracted with EA (3×20 mL), and the organic layer was washed with saturated NaCl aqueous solution, dried over anhydrous Na2SO4 and purified by flash chromatography to afford different 4-aminobiphenyl derivatives. According to the reductive amination procedure, the 4-aminobiphenyl derivative was further treated with salicylaldehyde and to afford the corresponding compound 5&6.

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2015,vol. 25,p. 3057 - 3061
[2]Journal of Medicinal Chemistry,2016,vol. 59,p. 2648 - 2659

56
[ 1204-79-1 ]
3-Hydroxy-6-((4′-hydroxy-[1,1′-biphenyl]-4-yl)amino)pyrimidine-2,4(1H,3H)-dione [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 2648 - 2659

57
[ 1204-79-1 ]
3-(benzyloxy)-6-chloropyrimidine-2,4(1H,3H)-dione [ No CAS ]
3-(benzyloxy)-6-((4'-hydroxy-[1,1'-biphenyl]-4-yl)amino)pyrimidine-2,4(1H,3H)-dione [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,2016,vol. 59,p. 2648 - 2659

58
[ 1527511-70-1 ]
[ 1204-79-1 ]

Reference： [1]Journal of the American Chemical Society,2017,vol. 139,p. 13821 - 13829

59
[ 71597-85-8 ]
[ 106-40-1 ]
[ 1204-79-1 ]

Reference： [1]Chemistry - A European Journal,2018,vol. 24,p. 9546 - 9554

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P244	Keep reduction valves free from grease and oil.
P250	Do not subject to grinding/shock/friction.
P251	Pressurized container: Do not pierce or burn, even after use.
P260	Do not breathe dust/fume/gas/mist/vapours/spray.
P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P262	Do not get in eyes, on skin, or on clothing.
P263	Avoid contact during pregnancy/while nursing.
P264	Wash hands thoroughly after handling.
P265	Wash skin thouroughly after handling.
P270	Do not eat, drink or smoke when using this product.
P271	Use only outdoors or in a well-ventilated area.
P272	Contaminated work clothing should not be allowed out of the workplace.
P273	Avoid release to the environment.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P281	Use personal protective equipment as required.
P282	Wear cold insulating gloves/face shield/eye protection.
P283	Wear fire/flame resistant/retardant clothing.
P284	Wear respiratory protection.
P285	In case of inadequate ventilation wear respiratory protection.
P231 + P232	Handle under inert gas. Protect from moisture.
P235 + P410	Keep cool. Protect from sunlight.
Response
Code	Phrase
P301	IF SWALLOWED:
P304	IF INHALED:
P305	IF IN EYES:
P306	IF ON CLOTHING:
P307	IF exposed:
P308	IF exposed or concerned:
P309	IF exposed or if you feel unwell:
P310	Immediately call a POISON CENTER or doctor/physician.
P311	Call a POISON CENTER or doctor/physician.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P313	Get medical advice/attention.
P314	Get medical advice/attention if you feel unwell.
P315	Get immediate medical advice/attention.
P320
P302 + P352	IF ON SKIN: wash with plenty of soap and water.
P321
P322
P330	Rinse mouth.
P331	Do NOT induce vomiting.
P332	IF SKIN irritation occurs:
P333	If skin irritation or rash occurs:
P334	Immerse in cool water/wrap n wet bandages.
P335	Brush off loose particles from skin.
P336	Thaw frosted parts with lukewarm water. Do not rub affected area.
P337	If eye irritation persists:
P338	Remove contact lenses, if present and easy to do. Continue rinsing.
P340	Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P341	If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342	If experiencing respiratory symptoms:
P350	Gently wash with plenty of soap and water.
P351	Rinse cautiously with water for several minutes.
P352	Wash with plenty of soap and water.
P353	Rinse skin with water/shower.
P360	Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P361	Remove/Take off immediately all contaminated clothing.
P362	Take off contaminated clothing and wash before reuse.
P363	Wash contaminated clothing before reuse.
P370	In case of fire:
P371	In case of major fire and large quantities:
P372	Explosion risk in case of fire.
P373	DO NOT fight fire when fire reaches explosives.
P374	Fight fire with normal precautions from a reasonable distance.
P376	Stop leak if safe to do so. Oxidising gases (section 2.4) 1
P377	Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P378
P380	Evacuate area.
P381	Eliminate all ignition sources if safe to do so.
P390	Absorb spillage to prevent material damage.
P391	Collect spillage. Hazardous to the aquatic environment
P301 + P310	IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P301 + P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P301 + P330 + P331	IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P302 + P334	IF ON SKIN: Immerse in cool water/wrap in wet bandages.
P302 + P350	IF ON SKIN: Gently wash with plenty of soap and water.
P303 + P361 + P353	IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P304 + P312	IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P304 + P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P304 + P341	IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P306 + P360	IF ON CLOTHING: Rinse Immediately contaminated CLOTHING and SKIN with plenty of water before removing clothes.
P307 + P311	IF exposed: call a POISON CENTER or doctor/physician.
P308 + P313	IF exposed or concerned: Get medical advice/attention.
P309 + P311	IF exposed or if you feel unwell: call a POISON CENTER or doctor/physician.
P332 + P313	IF SKIN irritation occurs: Get medical advice/attention.
P333 + P313	IF SKIN irritation or rash occurs: Get medical advice/attention.
P335 + P334	Brush off loose particles from skin. Immerse in cool water/wrap in wet bandages.
P337 + P313	IF eye irritation persists: Get medical advice/attention.
P342 + P311	IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.
P370 + P376	In case of fire: Stop leak if safe to Do so.
P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Purity	Size	Price	VIP Price	USA Stock *0-1 Day	Global Stock *5-7 Days	Quantity
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Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 1204-79-1 ]

Quality Control of [ 1204-79-1 ]

Related Doc. of [ 1204-79-1 ]

Product Details of [ 1204-79-1 ]

Safety of [ 1204-79-1 ]

Application In Synthesis of [ 1204-79-1 ]

[ 1204-79-1 ] Synthesis Path-Downstream 1~59

Related Functional Groups of [ 1204-79-1 ]

Aryls

Amines

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry

Related Functional Groups of
[ 1204-79-1 ]