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Chemical Structure| 120980-33-8 Chemical Structure| 120980-33-8

Structure of 120980-33-8

Chemical Structure| 120980-33-8

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Product Details of [ 120980-33-8 ]

CAS No. :120980-33-8
Formula : C22H18O4
M.W : 346.38
SMILES Code : O=C1CC(C2=CC=CC=C2)OC3=C1C(O)=CC(OCC4=CC=CC=C4)=C3

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Application In Synthesis of [ 120980-33-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 120980-33-8 ]

[ 120980-33-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 480-39-7 ]
  • [ 100-39-0 ]
  • [ 120980-33-8 ]
  • 2
  • [ 480-39-7 ]
  • [ 100-44-7 ]
  • [ 120980-33-8 ]
YieldReaction ConditionsOperation in experiment
89.0% To 100 ml acetone, 8.53 g (33 mmol) of a racemic <strong>[480-39-7]pinocembrin</strong> powder (obtained according to the method of DUAN Yabo et al, Chinese Journal of Medicinal Chemistry, 16(6):342-346, 2006) was added, stirred and dissolved, then 5 g (36 mmol) of K2CO3 powder and 0.31 g (1.88 mmol) of KI were added thereto, stirred for 5 minutes. 5 ml (43 mmol) of benzyl chloride was added, heated with an oil bath to reflux and monitored by TLC until the completion of the reaction (about 4 h).Then stopped heating, cooled to room temperature, inorganic salts were removed by filtration under a reduced pressure, the filter cake was washed fully with acetone, then the filtrate was collected, concentrated, and purified by a common silica gel column chromatography to give a pale yellow oil product, which was solidified with light petroleum to give a solid of benzyl protected racemic <strong>[480-39-7]pinocembrin</strong> (10.26 g, yield 89.0%).
 

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