[ CAS No. 121-01-7 ] {[proInfo.proName]}

Name: 121-01-7|4-Nitro-2-trifluoromethylaniline|98%
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2D 3D

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Quality Control of [ 121-01-7 ]

COA NMR CNMR HPLC LC-MS

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SDS Specification

Alternatived Products of [ 121-01-7 ]

Product Details of [ 121-01-7 ]

CAS No. :	121-01-7	MDL No. :	MFCD00007365
Formula :	C₇H₅F₃N₂O₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	HOTZLWVITTVZGY-UHFFFAOYSA-N
M.W :	206.12	Pubchem ID :	67128
Synonyms :

Calculated chemistry of [ 121-01-7 ]

Physicochemical Properties

Num. heavy atoms :	14
Num. arom. heavy atoms :	6
Fraction Csp3 :	0.14
Num. rotatable bonds :	2
Num. H-bond acceptors :	5.0
Num. H-bond donors :	1.0
Molar Refractivity :	44.67
TPSA :	71.84 Å²

Pharmacokinetics

GI absorption :	High
BBB permeant :	Yes
P-gp substrate :	No
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	No
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-6.22 cm/s

Lipophilicity

Log Po/w (iLOGP) :	1.15
Log Po/w (XLOGP3) :	1.89
Log Po/w (WLOGP) :	3.36
Log Po/w (MLOGP) :	1.37
Log Po/w (SILICOS-IT) :	0.03
Consensus Log Po/w :	1.56

Druglikeness

Lipinski :	0.0
Ghose :	None
Veber :	0.0
Egan :	0.0
Muegge :	0.0
Bioavailability Score :	0.55

Water Solubility

Log S (ESOL) :	-2.49
Solubility :	0.661 mg/ml ; 0.00321 mol/l
Class :	Soluble
Log S (Ali) :	-3.02
Solubility :	0.196 mg/ml ; 0.000953 mol/l
Class :	Soluble
Log S (SILICOS-IT) :	-2.31
Solubility :	1.0 mg/ml ; 0.00488 mol/l
Class :	Soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	3.0 alert
Leadlikeness :	1.0
Synthetic accessibility :	1.86

Safety of [ 121-01-7 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 121-01-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Upstream synthesis route of [ 121-01-7 ]
Downstream synthetic route of [ 121-01-7 ]

[ 121-01-7 ] Synthesis Path-Upstream 1~20

1
[ 98-46-4 ]
[ 121-01-7 ]
[ 400-98-6 ]

Reference： [1] Journal of Organic Chemistry, 1998, vol. 63, # 15, p. 4878 - 4888

2
[ 98-46-4 ]
[ 121-01-7 ]
[ 24821-17-8 ]
[ 400-98-6 ]

Reference： [1] Journal of Organic Chemistry, 1996, vol. 61, # 2, p. 442 - 443
[2] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 11, p. 1437 - 1444

3
[ 777-37-7 ]
[ 121-01-7 ]

Reference： [1] Tetrahedron, 2010, vol. 66, # 38, p. 7642 - 7650

[2] Patent: US2194926, 1937, ,
[3] Journal of Organic Chemistry, 1961, vol. 26, p. 2707 - 2710
[4] Journal of Organic Chemistry, 1962, vol. 27, p. 4660 - 4662

4
[ 98-46-4 ]
[ 121-01-7 ]

Reference： [1] Journal of Organic Chemistry, 1992, vol. 57, # 18, p. 4784 - 4785
[2] Journal of Organic Chemistry, 1998, vol. 63, # 15, p. 4878 - 4888

5
[ 1440512-30-0 ]
[ 121-01-7 ]

Reference： [1] Synlett, 2013, vol. 24, # 5, p. 652 - 656

6
[ 106860-28-0 ]
[ 98-46-4 ]
[ 121-01-7 ]
[ 393-11-3 ]

Yield	Reaction Conditions	Operation in experiment
85%	With sodium hydroxide In <i>N</i>-methyl-acetamide; methanol; ammonia; water	Example 8 Preparation of 4-nitro-2-trifluoromethylaniline A solution of 3.82 g (0.02 mol) of 3-trifluoromethylnitrobenzene, 3.3 g (0.02 mol) of N,N-diethylthiocarbamoylsulphenamide and 0.8 ml (0.02 mol) of methanol in 15 ml of dimethylformamide was added dropwise to a stirred suspension of 4 g (0.1 mol) of sodium hydroxide in 40 ml of dry liquid ammonia. During the addition the mixture was cooled externally to ensure only slight refluxing of ammonia. After the addition was complete (after 10 minutes) the mixture was stirred at -30° to -33° C. for 6 hours and ammonia was evaporated until the temperature of the mixture reached 0° C. The mixture was then cooled to -10° C. and 120 ml of water were added dropwise while keeping the temperature below +15° C. 3 ml of light petroleum were added to protect the mixture from exposure to air and the whole mixture was then stirred for 15 mins. and left to stand overnight. The precipitate was filtered and air-dried to give 3.5 g (85percent) of the product which had a melting point of 85°-89° C. It consisted of 92-93percent of the required 4-nitro-2-trifluoromethylaniline which was contaminated with 4-nitro-3-trifluoromethylaniline produced from the 2-trifluoromethylnitrobenzene which had contaminated the starting material.

Reference： [1] Patent: US5262539, 1993, A,

7
[ 98-46-4 ]
[ 121-01-7 ]
[ 400-98-6 ]

Reference： [1] Journal of Organic Chemistry, 1998, vol. 63, # 15, p. 4878 - 4888

8
[ 2926-29-6 ]
[ 100-01-6 ]
[ 121-01-7 ]

Reference： [1] Journal of Organic Chemistry, 2014, vol. 79, # 19, p. 8984 - 8989

9
[ 88-17-5 ]
[ 121-01-7 ]
[ 24821-17-8 ]

Reference： [1] Synthesis, 1989, # 10, p. 761 - 763

10
[ 98-46-4 ]
[ 121-01-7 ]
[ 24821-17-8 ]
[ 400-98-6 ]

Reference： [1] Journal of Organic Chemistry, 1996, vol. 61, # 2, p. 442 - 443
[2] Journal of the Chemical Society - Perkin Transactions 1, 1999, # 11, p. 1437 - 1444

11
[ 61349-99-3 ]
[ 121-01-7 ]

Reference： [1] ChemCatChem, 2018, vol. 10, # 5, p. 965 - 970

12
[ 88-16-4 ]
[ 121-01-7 ]

Reference： [1] Journal of Organic Chemistry, 1961, vol. 26, p. 2707 - 2710

13
[ 395-68-6 ]
[ 121-01-7 ]

Reference： [1] Journal of the Chemical Society, 1951, p. 3459,3463[2] Journal of the Chemical Society, 1954, p. 1071,1074

14
[ 344-62-7 ]
[ 121-01-7 ]

Reference： [1] Journal of the Chemical Society, 1951, p. 3459,3463[2] Journal of the Chemical Society, 1954, p. 1071,1074

15
[ 121-01-7 ]
[ 1548-61-4 ]

Reference： [1] Journal of Photochemistry and Photobiology A: Chemistry, 2011, vol. 226, # 1, p. 57 - 63

16
[ 121-01-7 ]
[ 19230-50-3 ]

Reference： [1] Journal of the Chemical Society, 1951, p. 3459,3463[2] Journal of the Chemical Society, 1954, p. 1071,1074

17
[ 121-01-7 ]
[ 367-67-9 ]

Reference： [1] Journal of Organic Chemistry, 1961, vol. 26, p. 2707 - 2710

18
[ 106860-28-0 ]
[ 98-46-4 ]
[ 121-01-7 ]
[ 393-11-3 ]

Yield	Reaction Conditions	Operation in experiment
85%	With sodium hydroxide In <i>N</i>-methyl-acetamide; methanol; ammonia; water	Example 8 Preparation of 4-nitro-2-trifluoromethylaniline A solution of 3.82 g (0.02 mol) of 3-trifluoromethylnitrobenzene, 3.3 g (0.02 mol) of N,N-diethylthiocarbamoylsulphenamide and 0.8 ml (0.02 mol) of methanol in 15 ml of dimethylformamide was added dropwise to a stirred suspension of 4 g (0.1 mol) of sodium hydroxide in 40 ml of dry liquid ammonia. During the addition the mixture was cooled externally to ensure only slight refluxing of ammonia. After the addition was complete (after 10 minutes) the mixture was stirred at -30° to -33° C. for 6 hours and ammonia was evaporated until the temperature of the mixture reached 0° C. The mixture was then cooled to -10° C. and 120 ml of water were added dropwise while keeping the temperature below +15° C. 3 ml of light petroleum were added to protect the mixture from exposure to air and the whole mixture was then stirred for 15 mins. and left to stand overnight. The precipitate was filtered and air-dried to give 3.5 g (85percent) of the product which had a melting point of 85°-89° C. It consisted of 92-93percent of the required 4-nitro-2-trifluoromethylaniline which was contaminated with 4-nitro-3-trifluoromethylaniline produced from the 2-trifluoromethylnitrobenzene which had contaminated the starting material.

Reference： [1] Patent: US5262539, 1993, A,

19
[ 121-01-7 ]
[ 341-58-2 ]

Reference： [1] Journal of the Chemical Society, 1951, p. 3459,3463[2] Journal of the Chemical Society, 1954, p. 1071,1074

20
[ 121-01-7 ]
[ 400-67-9 ]

Yield	Reaction Conditions	Operation in experiment
97%	With N-chloro-succinimide In acetonitrile at 150℃; for 0.25 h; Microwave irradiation	2-Chloro-4-nitro-6-trifluoromethylaniline; 4-Nitro-2-trifluoromethylaniline (15 g) and N-chlorosuccinimide (10.7 g) dissolved in acetonitril (100 ml) was heated to 150 0C for 15 minutes in a sealed microwave process vial. The reaction mixture was cooled to ambient temperature and poured into 5percent sodium hydroxide (500 ml) and ethylacetate (400 ml). After seperation the organic phase was dried (MgSO4), filtered and concentrated in vacuo, followed by purification by flash chromatography to furnish 17.0 g (97percent yield) of the title compound as a yellow solid. LC- MS (m/z) 240 (MH+); tR =4.76, (UV, ELSD) 97percent, 96percent. 1H NMR (500 MHz, DMSOd6): 7.15 (s, 2H), 8.15 (d, IH), 8.40 (d, IH).
75%	With N-chloro-succinimide In acetonitrile at 150℃; for 0.166667 h; Microwave	4-Nitro-2-trifluoromethyl-phenylamine (5.6 g) and N-chlorosuccinimide (4.0 g) were suspended in acetonitrile (15 mL) and heated to 150°C for 10 minutes in a sealed microwave process vial. Ethyl acetate (80 mL) was added and the organic phase was washed with 5percent aqueous NaOH (2x 50 mL), water (2x 50 mL) and brine (2x 50 mL). The organic phase was dried over magnesium sulfate and concentrated in vacuo. The crude product was purified by flash chromatography to furnish 4.9 g (75percent yield) of the title compound as a yellow solid.'H NMR (500 MHz, CDC13) : 5.35 (b, 2H), 8. 35 (b, 1H), 8.37 (b, 1H).

Reference： [1] Patent: WO2006/29623, 2006, A1, . Location in patent: Page/Page column 60-61
[2] Patent: WO2005/87754, 2005, A1, . Location in patent: Page/Page column 46
[3] Industrial and Engineering Chemistry, 1953, vol. 45, p. 1730,1732[4] Industrial and Engineering Chemistry, 1954, vol. 46, p. 2213,2218, 2219

[ 121-01-7 ] Synthesis Path-Downstream 1~87

1
[ 121-01-7 ]
[ 400-67-9 ]

Yield	Reaction Conditions	Operation in experiment
97%	With N-chloro-succinimide; In acetonitrile; at 150℃; for 0.25h;Microwave irradiation;	2-Chloro-4-nitro-6-trifluoromethylaniline; 4-Nitro-2-trifluoromethylaniline (15 g) and N-chlorosuccinimide (10.7 g) dissolved in acetonitril (100 ml) was heated to 150 0C for 15 minutes in a sealed microwave process vial. The reaction mixture was cooled to ambient temperature and poured into 5% sodium hydroxide (500 ml) and ethylacetate (400 ml). After seperation the organic phase was dried (MgSO4), filtered and concentrated in vacuo, followed by purification by flash chromatography to furnish 17.0 g (97% yield) of the title compound as a yellow solid. LC- MS (m/z) 240 (MH+); tR =4.76, (UV, ELSD) 97%, 96%. 1H NMR (500 MHz, DMSOd6): 7.15 (s, 2H), 8.15 (d, IH), 8.40 (d, IH).
75%	With N-chloro-succinimide; In acetonitrile; at 150℃; for 0.166667h;Microwave;	4-Nitro-2-trifluoromethyl-phenylamine (5.6 g) and N-chlorosuccinimide (4.0 g) were suspended in acetonitrile (15 mL) and heated to 150C for 10 minutes in a sealed microwave process vial. Ethyl acetate (80 mL) was added and the organic phase was washed with 5% aqueous NaOH (2x 50 mL), water (2x 50 mL) and brine (2x 50 mL). The organic phase was dried over magnesium sulfate and concentrated in vacuo. The crude product was purified by flash chromatography to furnish 4.9 g (75% yield) of the title compound as a yellow solid.'H NMR (500 MHz, CDC13) : 5.35 (b, 2H), 8. 35 (b, 1H), 8.37 (b, 1H).

Reference： [1]Patent: WO2006/29623,2006,A1 .Location in patent: Page/Page column 60-61
[2]Patent: WO2005/87754,2005,A1 .Location in patent: Page/Page column 46
[3]Industrial and Engineering Chemistry,1953,vol. 45,p. 1730,1732
Industrial and Engineering Chemistry,1954,vol. 46,p. 2213,2218, 2219

2
[ 121-01-7 ]
[ 400-75-9 ]

Yield	Reaction Conditions	Operation in experiment
94%	With sodium iodide; sodium nitrite; In sulfuric acid; water;	4-Iodo-3-trifluoromethyl-nitrobenzene To a mixture of 3.1 g (15.0 mmol) of 2-amino-5-nitrobenzotrifluoride in 60 mL of 40% (v/v) H2 SO4 stirred in an ice-bath was added dropwise a solution of 2.1 g (30.4 mmol) of NaNO2 in 10 mL of H2 O. The resulting yellow solution was stirred in an ice-bath for 1 h and it was added dropwise into a well stirred solution of 10 g of NaI in 250 mL of H2 O cooled in an ice bath. Gas releasing and precipitate was observed. The mixture was stirred overnight at 25 C., filtered and washed by water, and dried to leave pale yellow solid (4.5 g, 94%), mp 81-82 C. 1 H NMR (CDCl3), 8.047 (dd, 1), 8.272 (d, 1), 8.483 (d, 1).
	With CuI; sodium nitrite; In methanol; ice-water; H2SO4/H2O; water;	115a 4-Iodo-3-trifluoromethyl-nitrobenzene Under a protecting gas, 20 g (97 mmol) of 2-amino-5-nitrobenzotrifluoride (Fluka; Buchs, Switzerland) are placed in 250 ml of H2SO4/H2O 1:1 and cooled to 0 C., and at that temperature a solution of 6.69 g (97 mmol) of sodium nitrite in 39 ml of H2O is added. After 2 hours' stirring in an ice bath, 36.94 g (194 mmol) of CuI are added in portions, whereupon a light-yellow suspension forms. After 30 minutes, the mixture is heated slowly to 80 C. (vigorous evolution of gas!) and is stirred for one hour at 80 C. Pouring into one liter of ice-water and filtering off yield mustard-yellow crystals. They are extracted using 2*150 ml of methanol and in each case filtered. Concentration of the filtrates by evaporation, column chromatography (SiO2; toluene) and crystallisation from toluene yield the title compound: 1H NMR (DMSO-d6) 8.45 (d, J=8.6 Hz, 1H), 8.36 (d, J=2.7 Hz, 1H), 8.16 (dd, J=8.6/2.7 Hz, 1H); FAB-MS: (M)+=317; Anal. calc. (C7H3NO2F3I) C 26.52%, H 0.95%, N 4.42%,140.03%; C 26.53%, H 0.98%, N 4.50%, I 39.94%.

Reference： [1]Patent: US5514680,1996,A
[2]Journal of the Chemical Society,1951,p. 3459,3463
Journal of the Chemical Society,1954,p. 1071,1074
[3]Patent: US2002/10181,2002,A1
[4]Journal of Medicinal Chemistry,2009,vol. 52,p. 4869 - 4882

3
[ 121-01-7 ]
[ 400-66-8 ]

Yield	Reaction Conditions	Operation in experiment
91%	With bromine; In acetic acid; at 120℃; for 2.5h;	Bromine (0.60 mL) dissolved in acetic acid (11 mL) was added dropwise to a solution of 4-nitro-2-trifluoromethyl-phenylamine (2.4 g) in acetic acid (12 mL). The reaction mixture was heated to 120C for 2l/2 hours, poured into water (400 mL) and filtered. The collected solid was washed with water (200 mL) and dried in vacuo to furnish 3.03 g (91% yield) of the title compound as a yellow solid NMR (500 MHz, DMSO-d6): 7.08 (s, 2H), 8.23 (d, 1H), 8.51 (d, 1H).
91%	With bromine; acetic acid; at 120℃; for 2.5h;	2-Bromo-4-nitro-6-trifluoromethyl-phenylamine.; Bromine (0.60 mL) dissolved in acetic acid (11 mL) was added dropwise to a solution of 4-nitro-2-trifluoromethyl-phenylarnine (2.4 g) in acetic acid (12 mL). The reaction mixture was heated to 120 C for 21A hours, poured into water (400 mL) and filtered. The collected solid was washed with water (200 mL) and dried in vacuo to furnish 3.03 g (91% yield) of the title compound as a yellow solid. 1H NMR (500 MHz, DMSOd6): 7.08 (s, 2H), 8.23 (d, IH), 8.51 (d, IH).

Reference： [1]Journal of Chemical Research,2013,vol. 37,p. 197 - 200
[2]Patent: WO2005/87754,2005,A1 .Location in patent: Page/Page column 41
[3]Patent: WO2006/29623,2006,A1 .Location in patent: Page/Page column 58
[4]Journal of Organic Chemistry,1983,vol. 48,p. 2321 - 2327
[5]Industrial and Engineering Chemistry,1953,vol. 45,p. 1730,1732
Industrial and Engineering Chemistry,1954,vol. 46,p. 2213,2218, 2219

4
[ 1930-72-9 ]
[ 121-01-7 ]
[ 53446-58-5 ]

Reference： [1]Patent: FR2211450,1974,
Patent: DE2363602,1974,
Chem.Abstr.,1974,vol. 81

5
[ 121-01-7 ]
[ 2401-85-6 ]
[ 68105-51-1 ]

Reference： [1]Patent: DE2708440,1978,
Chem.Abstr.,1978,vol. 89

6
[ 121-01-7 ]
[ 16500-22-4 ]
4-Amino-1-hydroxy-N-[4-(2,4-di-tert-pentylphenoxy)butyl]-2-naphthamide [ No CAS ]
[ 54179-93-0 ]

Reference： [1]Patent: CH607103,1978,
Patent: DE2406653,1974,
Chem.Abstr.,1975,vol. 82

7
[ 121-01-7 ]
[ 2375-97-5 ]
[ 72773-11-6 ]

Reference： [1]Patent: DE2815290,1979,
Chem.Abstr.,1980,vol. 92

8
[ 98-46-4 ]
[ 121-01-7 ]

Reference： [1]Journal of Organic Chemistry,1992,vol. 57,p. 4784 - 4785
[2]Journal of Organic Chemistry,1998,vol. 63,p. 4878 - 4888

9
[ 121-01-7 ]
[ 92524-86-2 ]
[ 92524-78-2 ]

Reference： [1]Journal of Medicinal Chemistry,1985,vol. 28,p. 143 - 146

10
[ 117-80-6 ]
[ 121-01-7 ]
2-chloro-3-(4-nitro-2-trifluoromethyl-phenylamino)-[1,4]naphthoquinone [ No CAS ]
2,3-bis-(4-nitro-2-trifluoromethyl-phenylamino)-[1,4]naphthoquinone [ No CAS ]

Reference： [1]Synlett,2006,p. 942 - 944

11
[ 121-01-7 ]
[ 98-60-2 ]
4-chloro-4'-nitro-2'-trifluoromethylbenzenesulfonanilide [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry,2007,vol. 15,p. 1014 - 1021

12
[ 121-01-7 ]
<i>N</i>-(4-amino-2-trifluoromethyl-phenyl)-4-chloro-benzenesulfonamide [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry,2007,vol. 15,p. 1014 - 1021

13
[ 121-01-7 ]
N-(4-Amino-2-trifluoromethyl-phenyl)-2-fluoro-benzamide [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,p. 4157 - 4160

14
[ 121-01-7 ]
2-Fluoro-N-(4-{3-[1-(4-fluoro-phenyl)-ethyl]-thioureido}-2-trifluoromethyl-phenyl)-benzamide [ No CAS ]

Reference： [1]Bioorganic and Medicinal Chemistry Letters,2004,vol. 14,p. 4157 - 4160

15
[ 121-01-7 ]
4-[4-amino-2-(trifluoromethyl)phenylazo]triphenylamine [ No CAS ]

Reference： [1]Bulletin of the Chemical Society of Japan,2003,vol. 76,p. 607 - 612

16
[ 121-01-7 ]
4-[4-(4-nitrophenylazo)-2-(trifluoromethyl)phenylazo]triphenylamine [ No CAS ]

Reference： [1]Bulletin of the Chemical Society of Japan,2003,vol. 76,p. 607 - 612

17
[ 121-01-7 ]
4-{4-[4-nitro-2-(trifluoromethyl)phenylazo]-2-(trifluoromethyl)phenylazo}triphenylamine [ No CAS ]

Reference： [1]Bulletin of the Chemical Society of Japan,2003,vol. 76,p. 607 - 612

18
[ 121-01-7 ]
4-[4-pentafluorophenylazo-2-(trifluoromethyl)phenylazo]triphenylamine [ No CAS ]

Reference： [1]Bulletin of the Chemical Society of Japan,2003,vol. 76,p. 607 - 612

19
[ 121-01-7 ]
1-(4-amino-2-trifluoromethyl-phenyl)-pyrrolidine-2,5-dione [ No CAS ]

Reference： [1]Tetrahedron Letters,2003,vol. 44,p. 2133 - 2136

20
[ 121-01-7 ]
1-(4-amino-2-trifluoromethyl-phenyl)-piperidine-2,6-dione [ No CAS ]

Reference： [1]Tetrahedron Letters,2003,vol. 44,p. 2133 - 2136

21
[ 121-01-7 ]
[ 363-93-9 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

22
[ 121-01-7 ]
[ 393-04-4 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

23
[ 121-01-7 ]
[ 130206-38-1 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

24
[ 121-01-7 ]
[ 130206-16-5 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

25
[ 121-01-7 ]
[ 130206-39-2 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

26
[ 121-01-7 ]
[ 130206-17-6 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

27
[ 121-01-7 ]
4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-trifluoromethyl-benzenesulfonamide [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

28
[ 121-01-7 ]
{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-prop-2-ynyl-amino]-2-trifluoromethyl-benzenesulfonylamino}-acetic acid [ No CAS ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

29
[ 121-01-7 ]
[ 130206-44-9 ]

Reference： [1]Journal of Medicinal Chemistry,1996,vol. 39,p. 904 - 917

30
[ 121-01-7 ]
[ 85977-23-7 ]