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Chemical Structure| 1240737-77-2 Chemical Structure| 1240737-77-2

Structure of 1240737-77-2

Chemical Structure| 1240737-77-2

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Product Details of [ 1240737-77-2 ]

CAS No. :1240737-77-2
Formula : C16H31IN4O7
M.W : 518.34
SMILES Code : O=C(NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])CI
MDL No. :MFCD35598512

Safety of [ 1240737-77-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H315-H319
Precautionary Statements:P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235
Class:3
UN#:1993
Packing Group:

Application In Synthesis of [ 1240737-77-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1240737-77-2 ]

[ 1240737-77-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 39028-27-8 ]
  • [ 957486-82-7 ]
  • [ 1240737-77-2 ]
YieldReaction ConditionsOperation in experiment
0.44 g (60%) In 4-(dicyanomethylene)-2-methyl-6-(p-dimethylaminostyryl)-4H-pyran; Example 9a N-(20-azido-3,6,9,12,15,18-hexaoxaicosyl)-2-iodoacetamide (9a, N3-PEG6-IA) A solution of 20-azido-3,6,9,12,15,18-hexaoxaicosan-1-amine (NH2-PEG7-N3, 0.5 g, 1.43 mmol) and N-succinimidyl iodoacetate (0.4 g, 1.43 mmol) in DCM (5 mL) was stirred at room temperature for 2 h. The solvent was evaporated and the crude product was purified using flash chromatography on SiO2 with a 0-100% DCM/MeOH gradient to yield 0.44 g (60%) of 9a as a yellow oil; MS ESI (m/z): [M+H]+ calcd. for C16H32IO7N4, 519.34; found 519.4. 1H NMR (400 MHz, CDCl3): delta 3.39 (t, J=5.2 Hz, 2H), 3.44-3.48 (m, 2H), 3.58 (t, J=5.2 Hz, 2H), 3.63-3.69 (m, 22H), 3.74 (s, 2H), 7.10 (bs, 1H). 13C NMR (100.6 MHz, CDCl3): delta 26.0, 40.9, 51.3, 70.0, 70.6-71.3, 168.5 not clear
 

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