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[ CAS No. 124558-60-7 ] {[proInfo.proName]}

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Chemical Structure| 124558-60-7
Chemical Structure| 124558-60-7
Structure of 124558-60-7 * Storage: {[proInfo.prStorage]}
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Product Details of [ 124558-60-7 ]

CAS No. :124558-60-7 MDL No. :N/A
Formula : C14H8N2O8 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 332.22 Pubchem ID :-
Synonyms :

Safety of [ 124558-60-7 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 UN#:
Hazard Statements:H302-H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 124558-60-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 124558-60-7 ]

[ 124558-60-7 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 6662-72-2 ]
  • [ 124558-60-7 ]
YieldReaction ConditionsOperation in experiment
92% With chromium(VI) oxide; sulfuric acid; at 20 - 50℃; for 0.26h; 2,2'-6,6'-tetramethyl-4,4'-bipyridine 2 g (9.4 mmol) was dispersed in 96% concentrated sulfuric acid 25 mL, and 11.2 g of chromium trioxide (0.11 mol) was divided into small Add a portion of concentrated sulfuric acid solution,Add it in about 30min. Stirring was continued for 24 h at room temperature and heating to 50 C for 2 h.About 20 g of ice was added directly to the reaction mixture. Precipitating a white precipitate,The mixture was cooled to -5 C and the remaining chromic acid solution was removed by rapid centrifugation.The solid was suction filtered, and the solid was quickly washed with 2 mL of cold water and dried to yield white powder 2.9 g, yield: 92%.
  • 2
  • [ 67-56-1 ]
  • [ 124558-60-7 ]
  • [ 124558-62-9 ]
YieldReaction ConditionsOperation in experiment
98% With sulfuric acid for 4h; Heating;
85% With thionyl chloride at 0℃; for 6h; Reflux;
  • 3
  • [ 64-17-5 ]
  • [ 124558-60-7 ]
  • [ 124558-63-0 ]
YieldReaction ConditionsOperation in experiment
96% With sulfuric acid for 2h; Heating;
  • 4
  • [ 124558-60-7 ]
  • [ 124558-61-8 ]
YieldReaction ConditionsOperation in experiment
90% With thionyl chloride; N,N-dimethyl-formamide for 4h; Heating;
65% With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 17h; Heating;
With thionyl chloride for 5h; Reflux; Inert atmosphere;
  • 5
  • [ 108-48-5 ]
  • [ 124558-60-7 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 40 percent / Na / toluene; various solvent(s); tetrahydrofuran 2: 70 percent / sulfuric acid; chromium trioxide / 2 h / 75 °C
Multi-step reaction with 3 steps 1: sodium / tetrahydrofuran / 30 °C / Inert atmosphere 2: air / water / 0.25 h / 50 °C 3: sulfuric acid; chromium(VI) oxide / 0.26 h / 20 - 50 °C
Multi-step reaction with 2 steps 1.1: sodium / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere 1.2: 2 h / Inert atmosphere 2.1: sulfuric acid; potassium dichromate
  • 6
  • [ 124558-60-7 ]
  • [ 7732-18-5 ]
  • [ CAS Unavailable ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
76% With 2,6-lutidine In water High Pressure; sealed in a bomb, heated at a rate of 1°C/min up to 130°C,kept at this temp. for 6 d; left to cool to room temp., filtered, washed (H2O, EtOH, Et2O), dried (air); elem. anal.;
31% With 1,3,5-tris(4-pyridyl)benzene In water High Pressure; sealed in a bomb, heated slowly up to 130°C, kept at this temp. for 6 d; cooled to room temp. at a rate of 0.2°C/min, filtered, washed (H2O, EtOH, Et2O);
With NaOH or C5H5N or (C2H5)3N or NH(CH(CH3)2)2 In water High Pressure; at 110-150°C;
  • 7
  • [ 124558-60-7 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: NaOH or C5H5N or (C2H5)3N or NH(CH(CH3)2)2 / water 2: neat (no solvent)
  • 8
  • [ CAS Unavailable ]
  • [ 124558-60-7 ]
  • [ 7732-18-5 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
90% With triethylamine at 180℃; for 96h; Autoclave;
  • 9
  • [ 2623-87-2 ]
  • [ 124558-60-7 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
70% In N,N-dimethyl-formamide for 0.166667h; Sealed tube; Microwave irradiation; 10 Example 10 First, 2,2',6,6'-tetracarboxy-4,4'-bipyridine (1 equiv.), 3-bromo-1-butyric acid (10 equiv.) and appropriate amount of N,N dimethylformamide were mixed until solid All dissolved. The mixed liquid was put into a sealed quartz tube, the quartz tube was placed in a microwave oven, and heated for 10 min at a power of 60 W, and the reactants were cooled and filtered. Then it was washed three times with N,N dimethylformamide solution, and finally vacuum-dried to obtain a powder named bis(3carboxy-propyl)-2,2',6,6'-tetracarboxy-4,4'- Bipyridine, yield: 70%.
  • 10
  • [ 124558-60-7 ]
  • [ 627-18-9 ]
  • [ 2767216-41-9 ]
YieldReaction ConditionsOperation in experiment
70% In N,N-dimethyl-formamide for 0.0833333h; Sealed tube; Microwave irradiation; 6 Example 6 First, 2,2',6,6'-tetracarboxy-4,4'-bipyridine (1 equiv.), 3-bromo-1-propanol (10 equiv.) and appropriate amount of N,N dimethylformamide were mixed until solid All dissolved. The mixed liquid was put into a sealed quartz tube, and the quartz tube was placed in a microwave oven, heated at 100 W for 5 min, paused for 30 s, then heated for 5 min, and the reactant was cooled and filtered. Then it was washed 3 times with N,N dimethylformamide solution, and finally vacuum-dried to obtain a powder named bis(3hydroxy-propyl)-2,2',6,6'-tetracarboxy-4,4'- Bipyridine, yield: 70%.
  • 11
  • [ 124558-60-7 ]
  • [ 627-18-9 ]
  • [ 2767216-44-2 ]
YieldReaction ConditionsOperation in experiment
60% Stage #1: [4,4'-bipyridine]-2,2',6,6'-tetracarboxylic acid; 1-bromo-3-propanol In acetonitrile for 0.0833333h; Sealed tube; Microwave irradiation; Stage #2: With 1,3-propanesultone In N,N-dimethyl-formamide for 0.05h; Sealed tube; Microwave irradiation; 8 Example 8 First, 2,2'-dicarboxy, 6,6'-dimethyl-4,4'-bipyridine (1 equiv), 3-bromo-1-propanol (1 equiv) and appropriate amount of acetonitrile were mixed until all were estimated to dissolve, The mixed liquid was put into a sealed quartz tube, the quartz tube was placed in a microwave oven, and heated for 5 min at a power of 60W, and the reactants were cooled and filtered. It was then washed three times with toluene solution, and finally dried under vacuum to obtain a powder. Dissolve the powder in anhydrous N,N dimethylformamide solution, add propyl sultone (2 equiv.), put the mixed solution into a sealed quartz tube, put the quartz tube in a microwave oven, and put it in a microwave oven at 100W. Under power, heat for 3 min, and the reactant is cooled and filtered. Then washed 3 times with N,N dimethylformamide solution, and finally vacuum dried to obtain a powder named 3-hydroxy-propyl-3-sulfonic acid-propyl-2,2'-dicarboxy-,6,6' - Dimethyl-4,4'-bipyridine, yield: 60%.
  • 12
  • [ 124558-60-7 ]
  • [ CAS Unavailable ]
YieldReaction ConditionsOperation in experiment
95 % With sodium hydroxide In water at 20℃;
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