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Chemical Structure| 1262619-30-6 Chemical Structure| 1262619-30-6

Structure of 1262619-30-6

Chemical Structure| 1262619-30-6

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Product Details of [ 1262619-30-6 ]

CAS No. :1262619-30-6
Formula : C11H10ClN3O2S
M.W : 283.73
SMILES Code : CS(=O)(NC1=CC=C(C2=NN=C(Cl)C=C2)C=C1)=O
MDL No. :MFCD26393079

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Application In Synthesis of [ 1262619-30-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1262619-30-6 ]

[ 1262619-30-6 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 141-30-0 ]
  • [ 380430-57-9 ]
  • [ 1262619-30-6 ]
YieldReaction ConditionsOperation in experiment
With sodium carbonate;tetrakis(triphenylphosphine) palladium(0); In 1,2-dimethoxyethane; at 85℃; for 22h;Inert atmosphere; To a round bottom flask was added 3,6-dichloropyridazine (20.1 mmole), 4-(methylsulfonylamino)phenylboronic acid (20.1 mmole), tetrakis(triphenylphosphine)palladium (1.00 mmole), 2M Na2CO3 (30 mL), and 1,2-dimethoxyethane (120 mL). The resulting reaction mixture was heated at 85 C for 22 hours. The reaction mixture was diluted with ethyl acetate and filtered through celite. The filtrate was washed with water. The organic extract was dried over Na2SO4 and evaporated in vacuo. The crude residue was purified by biotage column chromatography eluting with 4:1 ethyl acetate to hexane mixture to afford N-(4-(6-chloropyridazin-3-yl)phenyl)methanesulfonamide.
 

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