Alternatived Products of [ 1268631-42-0 ]
Product Details of [ 1268631-42-0 ]
CAS No. : | 1268631-42-0 |
MDL No. : | N/A |
Formula : |
C9H11BO2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
161.99
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 1268631-42-0 ]
Application In Synthesis of [ 1268631-42-0 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1268631-42-0 ]
- 1
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[ 1268631-42-0 ]
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[ 183267-04-1 ]
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[ 1994357-25-3 ]
Yield | Reaction Conditions | Operation in experiment |
72% |
With [2,2]bipyridinyl; copper (I) iodide; anhydrous sodium carbonate In acetonitrile at 60℃; for 12h; Inert atmosphere; stereospecific reaction; |
(II) General procedure for copper(I)-Promoted Triuoromethylthiolation of Styreneboronic acid with N-trifluoromethylthiosuccinimide
General procedure: To a 25 mL flask charged with aryl vinyl boric acid (1.0 equiv, 0.3 mmol), N-trifluoromethylthiosuccinimide (1.5 equiv), CuI (10 mmol%), Na2CO3 (4.0 equiv) and bpy (20 mmol%) was slowly added CH3CN (5 mL) by syringe at room temperature under N2 atmosphere. The reaction mixture was stirred at 60 °C for 12 hours (monitored by TLC). After cooling to room temperature, the suspension was filtered through a short pad of celite and the adsorbent was washed with DCM (2×5 mL). Then the filtrate was further washed with water (10 mL) and saturated NaCl solution (10 mL), dried over Na2SO4 and concentrated under vacuum. The residue was purified by silica gel flash column chromatography using EtOAc/PE (V/V = 1/15) as eluent to afford the products. |
Reference:
[1]Zheng, Changge; Ma, Mingyu; Huang, Shuai; Jiang, Chao; Liu, Yang; Fu, Yingying; Zhao, Kui; Feng, Ruilong; Hong, Jianquan
[Tetrahedron Letters, 2022, vol. 103]