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Chemical Structure| 127-79-7 Chemical Structure| 127-79-7

Structure of Sulfamerazine
CAS No.: 127-79-7

Chemical Structure| 127-79-7

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Sulfamerazine is a sulfanilamide antibacterial agent working by inhibiting bacterial synthesis of dihydrofolic acid through competing with PABA (para-aminobenzoic acid) for binding to dihydropteroate synthetase (dihydrofolate synthetase).

Synonyms: RP2632

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Product Details of Sulfamerazine

CAS No. :127-79-7
Formula : C11H12N4O2S
M.W : 264.30
SMILES Code : CC1=NC(NS(=O)(C2=CC=C(N)C=C2)=O)=NC=C1
Synonyms :
RP2632
MDL No. :MFCD00023212
InChI Key :QPPBRPIAZZHUNT-UHFFFAOYSA-N
Pubchem ID :5325

Safety of Sulfamerazine

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

In Vitro:

Cell Line
Concentration Treated Time Description References
Kiwi pollen 0.005 mol/dm3 24 and 48 hours Evaluate the effect of sulfamerazine combined with β-cyclodextrin on pollen germination, showing positive effects. Biomolecules. 2024 Apr 10;14(4):462
BY-2 tobacco cells 0.005 mol/dm3 7 days Evaluate the effect of sulfamerazine combined with β-cyclodextrin on cell growth, showing positive effects. Biomolecules. 2024 Apr 10;14(4):462

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.78mL

0.76mL

0.38mL

18.92mL

3.78mL

1.89mL

37.84mL

7.57mL

3.78mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

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