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Chemical Structure| 127984-93-4 Chemical Structure| 127984-93-4

Structure of 127984-93-4

Chemical Structure| 127984-93-4

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Product Details of [ 127984-93-4 ]

CAS No. :127984-93-4
Formula : C4H4BrN3O2
M.W : 206.00
SMILES Code : O=C(N1)N(N)C=C(Br)C1=O
MDL No. :MFCD00673944

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Application In Synthesis of [ 127984-93-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 127984-93-4 ]

[ 127984-93-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 58042-39-0 ]
  • [ 33282-64-3 ]
  • [ 127984-93-4 ]
YieldReaction ConditionsOperation in experiment
55% In dichloromethane; water; SYNTHESIS EXAMPLE 2 1-Amino-5-bromouracil After the silylation of 5-bromouracil conducted in the same manner as in Synthesis Example 1, 8.8 g (26 mmole) of 5-bromo-2,4-ditrimethylsilyloxypyrimidine distilled and purified was dissolved in 50 ml of dichloromethane. To the solution was added 6.7 g (31 mmole) of <strong>[58042-39-0]MSH</strong> under ice-cooling, and the mixture was reacted with stirring at room temperature for 4 hours. After reaction, the reaction solution was concentrated under reduced pressure. To the residue were added distilled water (200 ml) and subsequently 2N-sodium hydroxide to adjust the pH to 6.0, and the solution was concentrated under reduced pressure. The crude product thus obtained was collected by filtration and recrystallized from 50% ethanol to give 3 g (yield, 55%) of crystalline 1-amino-5-bromouracil. M.P.: 214-215 C. Elementary analysis for C4 H4 N3 O2 Br;
 

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