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Chemical Structure| 1285094-14-5 Chemical Structure| 1285094-14-5

Structure of 1285094-14-5

Chemical Structure| 1285094-14-5

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Product Details of [ 1285094-14-5 ]

CAS No. :1285094-14-5
Formula : C14H10Cl2O2
M.W : 281.13
SMILES Code : CC(C1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)=O
MDL No. :MFCD02110474

Safety of [ 1285094-14-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1285094-14-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1285094-14-5 ]

[ 1285094-14-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 2923-66-2 ]
  • [ 106-48-9 ]
  • [ 1285094-14-5 ]
YieldReaction ConditionsOperation in experiment
83% With potassium carbonate; In 1-methyl-pyrrolidin-2-one; at 100℃; for 5.5h; Step 1 A solution of <strong>[2923-66-2]1-(3-chloro-4-fluoro-phenyl)ethanone</strong> (100.3 g, 0.58 mol), 4-chlorophenol (91.6 g, 0.71 mol) and K2CO3 (97.7 g, 0.72 mol) in NMP (1 L) was heated for 5.5 h at 100 C. After dilution of the reaction mixture with MTBE, the organic phase was washed 5 times with water, concentrated and dried. The yellow oil was purified by recrystallization with diisopropylether (200 mL) over weekend to give 1-[3-chloro-4-(4-chlorophenoxy)phenyl]ethanone as a pale yellow powder (135.2 g, 83%).
 

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