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Chemical Structure| 130021-87-3 Chemical Structure| 130021-87-3

Structure of 130021-87-3

Chemical Structure| 130021-87-3

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Product Details of [ 130021-87-3 ]

CAS No. :130021-87-3
Formula : C7H9NS2
M.W : 171.28
SMILES Code : CN(C(C1=CSC=C1)=S)C

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Application In Synthesis of [ 130021-87-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 130021-87-3 ]

[ 130021-87-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6964-21-2 ]
  • [ 33513-42-7 ]
  • [ 130021-87-3 ]
YieldReaction ConditionsOperation in experiment
66% With potassium carbonate; sulfur; at 120℃; for 24h; General procedure: Elemental sulfur powder (S8, Mol. wt 32, 4 mmol) and K2CO3 (2 equiv) were added to a vial (10 mL) containing phenylacetic acid 1 or cinnamic acid 4 (1 mmol) and DMF (1 mL). The reaction mixture was heated at 120/100 C in an oil bath for 24 h. After completion of the reaction as determined by TLC, reaction mixture was allowed to cool to room temperature, diluted with water and then extracted with ethyl acetate (3*10 mL). The combined organic phase was evaporated under reduced pressure, and the resulting crude was separated through column chromatography using hexane-ethyl acetate as an eluent to afford the pure product 3/5. The formation of the products 7, however, required the use of DMSO for smooth reaction. 4.1.9. N,N-Dimethylthiophene-3-carbothioamide (3i). 11a Yellow oil; yield (66%, 112 mg); 1H NMR (CDCl3, 300 MHz): δ 7.35 (s, 1H), 7.25-7.28 (m, 1H), 7.13 (d, J=5.1 Hz, 1H), 3.55 (s, 3H), 3.26 (s, 3H); 13C NMR (75 MHz, CDCl3): δ 195.0, 142.9, 126.9, 125.3, 123.6, 43.9, 43.1.
 

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