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Chemical Structure| 1301212-43-0 Chemical Structure| 1301212-43-0

Structure of 1301212-43-0

Chemical Structure| 1301212-43-0

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Product Details of [ 1301212-43-0 ]

CAS No. :1301212-43-0
Formula : C7H7N3S
M.W : 165.22
SMILES Code : NC1=C2C(C(C)=CS2)=NC=N1

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Application In Synthesis of [ 1301212-43-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1301212-43-0 ]

[ 1301212-43-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 175137-21-0 ]
  • [ 1301212-43-0 ]
YieldReaction ConditionsOperation in experiment
78% With ammonium hydroxide; In butan-1-ol; at 90℃; for 4h;Sealed tube; EXAMPLE 28; (3R,4R)-N-(7-Methylthieno[3,2-d]pyrimidin-4-yl)-4'H-l- azaspiro[bicyclo[2.2.1 heptane-3, 5 '-οχαζο J -2 '-amine; Step A: 7-Methylthieno[3,2-d]pyrim; In a sealed tube was added <strong>[175137-21-0]4-chloro-7-methylthieno[3,2-d]pyrimidine</strong> (2.0 g, 10.83 mmol) and ammonium hydroxide (12.65 mmol, 325 mmol) in butanol (7ml). The reaction was heated to 90C for 4 hours and then cooled to room temperature. The resulting white precipitate was collected to give 7-methylthieno[3,2-d]pyrimidin 4-amine (1.4 g, 78% yield). 1H NMR (400 MHz, DMSO-d6) δ ppm 8.41 (1 H, s), 7.74 (1 H, s), 7.34 (2 H, s), 2.34 (3 H, d, J=1.00 Hz).
 

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